专利检索 ap:("Nantbio, Inc.") AND inv:"David G. Ho" 第 1 页

1.

发明申请
COMPOSITIONS AND METHODS OF TARGETING MUTANT K-RAS 审中-公开

公开(公告)号：US20180201610A1

公开(公告)日：2018-07-19

申请号：US15874485

申请日：2018-01-18

申请人： Nantbio, Inc.

发明人： Chunlin Tao , Laxman Nallan , David G. Ho , Qinwei Wang , Paul Weingarten , Anna B. Juncker-Jensen

IPC分类号： C07D417/14 , A61P35/00

CPC分类号： C07D417/14 , A61P35/00

摘要： Compounds and compositions are presented that inhibit K-Ras, and especially mutant K-Ras. Certain compounds preferentially or even selectively inhibit specific forms of mutant K-Ras, and particularly the G12D mutant form.

2.

发明授权
Compositions and methods of targeting mutant K-ras 有权

公开(公告)号：US10344026B2

公开(公告)日：2019-07-09

申请号：US15874485

申请日：2018-01-18

申请人： NANTBIO, INC.

发明人： Chunlin Tao , Laxman Nallan , David G. Ho , Qinwei Wang , Paul Weingarten , Anna B. Juncker-Jensen

IPC分类号： A61P35/00 , C07D417/14

摘要： Compounds and compositions are presented that inhibit K-Ras, and especially mutant K-Ras. Certain compounds preferentially or even selectively inhibit specific forms of mutant K-Ras, and particularly the G12D mutant form.