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公开(公告)号:US07378492B2
公开(公告)日:2008-05-27
申请号:US10504973
申请日:2003-02-18
申请人: Narinder K. Chawla , Henry Yue , Thomas W. Richardson , Joseph P. Marquis , Patricia M. Lehr-Mason , Ann E. Gorvad , Shanya D. Becha , Amy E. Kable , Anita Swarnakar , Pei Jin , Phillip R. Hawkins , David Chien , Jayalaxmi Ramkumar , Uyen K. Tran , April J. A. Hafalia , Mariah R. Baughn , Soo Yeun Lee , Xin Jiang , Alan A. Jackson , Reena Khare , Sean A. Bulloch
发明人: Narinder K. Chawla , Henry Yue , Thomas W. Richardson , Joseph P. Marquis , Patricia M. Lehr-Mason , Ann E. Gorvad , Shanya D. Becha , Amy E. Kable , Anita Swarnakar , Pei Jin , Phillip R. Hawkins , David Chien , Jayalaxmi Ramkumar , Uyen K. Tran , April J. A. Hafalia , Mariah R. Baughn , Soo Yeun Lee , Xin Jiang , Alan A. Jackson , Reena Khare , Sean A. Bulloch
IPC分类号: C07K14/705 , C07K19/00
CPC分类号: C07K14/705 , C07K16/28
摘要: Various embodiments of the invention provide human receptors and membrane-associated proteins (REMAP) and Q polynucleotides which identify and encode REMAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of REMAP.
摘要翻译: 本发明的各种实施方案提供鉴定和编码REMAP的人受体和膜相关蛋白(REMAP)和Q多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其他实施方案提供用于诊断,治疗或预防与REMAP异常表达相关的紊乱的方法。