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公开(公告)号：US20070225218A1
公开(公告)日：2007-09-27
申请号：US10481700
申请日：2002-06-26
申请人： Angelo Delegeane , Mark Borowsky , Farrah Khan , Liam Kearney , Jayalaxmi Ramkumar , Narinder Chawla , Yan Lu , Cynthia Honchell , Deborah kallick , Brooke Emerling , Ann Gorvard , Jennifer Griffin , Bridget Warren , Henry Yue , Kavitha Thangavelu , William Sprague , Craig Ison , Vicki Elliott , Patricia Lehr-Mason , Thomas Richardson , Uyen Tran , Anita Swarnakar , Pei Jin , Amy Kable
发明人： Angelo Delegeane , Mark Borowsky , Farrah Khan , Liam Kearney , Jayalaxmi Ramkumar , Narinder Chawla , Yan Lu , Cynthia Honchell , Deborah kallick , Brooke Emerling , Ann Gorvard , Jennifer Griffin , Bridget Warren , Henry Yue , Kavitha Thangavelu , William Sprague , Craig Ison , Vicki Elliott , Patricia Lehr-Mason , Thomas Richardson , Uyen Tran , Anita Swarnakar , Pei Jin , Amy Kable
IPC分类号： C12P21/00 , A61K38/00 , C07H21/04 , C07K14/00 , C12Q1/68 , G01N33/53 , C07K16/18 , C12N15/00 , C12N5/06
摘要： Various embodiments of the invention provide human extracellular messengers (EXMES) and polynucleotides which identify and encode EXMES. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of EXMES.
摘要翻译： 本发明的各种实施方案提供了识别和编码EXMES的人细胞外信使（EXMES）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其它实施方案提供用于诊断，治疗或预防与异常表达EXMES相关的紊乱的方法。
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公开(公告)号：US20070009516A1
公开(公告)日：2007-01-11
申请号：US10535635
申请日：2003-11-25
申请人： Uyen Tran , Thomas Richardson , Shanya Becha , Vicki Elliott , Anita Swarnakar , Soo Lee , Jayalaxmi Ramkumar , Jonathan Wang , David Chien , Jagi Murage , Mili Gera , Joseph Marquis , Narinder Chawla , Lisa Nakamura , Amy Kable
发明人： Uyen Tran , Thomas Richardson , Shanya Becha , Vicki Elliott , Anita Swarnakar , Soo Lee , Jayalaxmi Ramkumar , Jonathan Wang , David Chien , Jagi Murage , Mili Gera , Joseph Marquis , Narinder Chawla , Lisa Nakamura , Amy Kable
IPC分类号： C12Q1/68 , C07H21/04 , C12P21/06 , A61K39/395 , C12M1/34 , A01K67/00 , C07K14/705 , C07K16/28
CPC分类号： C07K14/47
摘要： Various embodiments of the invention provide human immune response associated proteins (IRAP) and polynucleotides which identify and encode IRAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of IRAP.
摘要翻译： 本发明的各种实施方案提供鉴定和编码IRAP的人免疫应答相关蛋白（IRAP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与IRAP异常表达相关的紊乱的方法。
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公开(公告)号：US06927056B2
公开(公告)日：2005-08-09
申请号：US10363937
申请日：2001-09-06
申请人： Stephen Todd , Angelo M. Delegeane , Ameena R. Gandhi , Danniel B. Nguyen , April J. A. Hafalia , Liam Kearney , Yan Lu , Ernestine A. Lee , Narinder K. Chawla , Debopriya Das , Chandra S. Arvizu , Monique G. Yao , Deborah A. Kallick , Vicki S. Elliott , Li Ding , Henry Yue , Roopa M. Reddy , Dyung Aina M. Lu , Jayalaxmi Ramkumar , Junming Yang , Catherine M. Tribouley , Neil Burford , Mariah R. Baughn , Preeti G. Lal , Mark L. Borowsky , Farrah A. Khan , Rajagopal Gururajan , Y. Tom Tang , Janice K. Au-Young , Bridget A. Warren , Roberto Hernandez , Brendan M. Duggan
发明人： Stephen Todd , Angelo M. Delegeane , Ameena R. Gandhi , Danniel B. Nguyen , April J. A. Hafalia , Liam Kearney , Yan Lu , Ernestine A. Lee , Narinder K. Chawla , Debopriya Das , Chandra S. Arvizu , Monique G. Yao , Deborah A. Kallick , Vicki S. Elliott , Li Ding , Henry Yue , Roopa M. Reddy , Dyung Aina M. Lu , Jayalaxmi Ramkumar , Junming Yang , Catherine M. Tribouley , Neil Burford , Mariah R. Baughn , Preeti G. Lal , Mark L. Borowsky , Farrah A. Khan , Rajagopal Gururajan , Y. Tom Tang , Janice K. Au-Young , Bridget A. Warren , Roberto Hernandez , Brendan M. Duggan
IPC分类号： A01K67/00 , C07H21/04 , C12N9/64 , C12N15/09 , C12P21/06 , C12Q1/68 , C12N1/20 , C12N15/00 , C12N15/63
CPC分类号： C12N9/6421 , A01K2217/05 , A01K2217/075 , C07H21/04 , C12N9/6472 , C12Q1/6837 , C12Q1/6883 , C12Q2600/156 , C12Q2600/158 , Y02A50/52
摘要： The invention provides a human cysteine proteases and polynucleotides which encode those proteases. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists, as well as methods for diagnosing, treating, or preventing disorders associated with aberrant expression of cysteine proteases.
摘要翻译： 本发明提供编码这些蛋白酶的人半胱氨酸蛋白酶和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂，以及用于诊断，治疗或预防与半胱氨酸蛋白酶异常表达相关的紊乱的方法。
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公开(公告)号：US20050118582A1
公开(公告)日：2005-06-02
申请号：US10483505
申请日：2002-07-10
申请人： Anita Swarnakar , Thomas Richardson , Bridget Warren , Jennifer Griffin , Y Tang , Henry Yue , Mariah Baughn , Brooke Emerling , Preeti Lal , Dyung Lu , Ian Forsythe , Jayalaxmi Ramkumar , Joana Li , Shanya Becha , Brendan Duggan , Madhusudan Sanjanwala , Ernestine Lee , Neil Burford , Vicki Elliott , Craig Ison , Li Ding , Mark Borowsky , Monique Yao , Ines Barroso , Bao Tran , Narinder Chawla , April Hafalia , Danniel Nguyen , Yan Lu , Chandra Arvizu
发明人： Anita Swarnakar , Thomas Richardson , Bridget Warren , Jennifer Griffin , Y Tang , Henry Yue , Mariah Baughn , Brooke Emerling , Preeti Lal , Dyung Lu , Ian Forsythe , Jayalaxmi Ramkumar , Joana Li , Shanya Becha , Brendan Duggan , Madhusudan Sanjanwala , Ernestine Lee , Neil Burford , Vicki Elliott , Craig Ison , Li Ding , Mark Borowsky , Monique Yao , Ines Barroso , Bao Tran , Narinder Chawla , April Hafalia , Danniel Nguyen , Yan Lu , Chandra Arvizu
CPC分类号： C07K14/4702
摘要： Various embodiments of the invention provide human nucleic acid-associated proteins (NAAP) and polynucleotides which identify and encode NAAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NAAP.
摘要翻译： 本发明的各种实施方案提供了识别和编码NAAP的人核酸相关蛋白（NAAP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与NAAP异常表达相关的紊乱的方法。
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公开(公告)号：US20050019763A1
公开(公告)日：2005-01-27
申请号：US10473451
申请日：2002-04-05
申请人： Ameena Gandhi , Angelo Delegeane , Anita Swarnakar , April Hafalia , Brendan Duggan , Bridget Warren , Brooke Emerling , Chandra Arvizu , Cynthia Honchell , Deborah Kallick , Dyung Lu , Ernestine Lee , Henry Yue , Ian Forsythe , Jayalaxmi Ramkumar , Jennifer Griffin , Joana Li , Kavitha Thangavelu , Mariah Baughn , Monique Yao , Madhusudan Sanjanwala , Narinder Chawla , Neil Burford , Preeti Lal , Shanya Becha , Soo Lee , Vicki Elliott , Wen Luo , Yan Lu , Yu-mei Wang
发明人： Ameena Gandhi , Angelo Delegeane , Anita Swarnakar , April Hafalia , Brendan Duggan , Bridget Warren , Brooke Emerling , Chandra Arvizu , Cynthia Honchell , Deborah Kallick , Dyung Lu , Ernestine Lee , Henry Yue , Ian Forsythe , Jayalaxmi Ramkumar , Jennifer Griffin , Joana Li , Kavitha Thangavelu , Mariah Baughn , Monique Yao , Madhusudan Sanjanwala , Narinder Chawla , Neil Burford , Preeti Lal , Shanya Becha , Soo Lee , Vicki Elliott , Wen Luo , Yan Lu , Yu-mei Wang
IPC分类号： G01N33/50 , A61K38/00 , A61K45/00 , A61K49/00 , A61P1/00 , A61P9/00 , A61P15/00 , A61P25/00 , A61P29/00 , A61P35/00 , A61P37/06 , A61P43/00 , C07K14/47 , C07K16/18 , C12M1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/64 , C12N15/09 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N37/00 , A01K67/00 , C07H21/04
CPC分类号： C12N9/6421 , A01K2217/05 , A61K38/00
摘要： The invention provides human protein modification and maintenance molecules (PMOD) and polynucleotides which identify and encode PMOD. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PMOD.
摘要翻译： 本发明提供了鉴定和编码PMOD的人蛋白质修饰和维持分子（PMOD）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供了用于诊断，治疗或预防与PMOD异常表达相关的紊乱的方法。
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公开(公告)号：US20080241158A1
公开(公告)日：2008-10-02
申请号：US11896125
申请日：2007-08-29
申请人： Preeti G. Lal , Richard C. Graul , April J.A. Hafalia , Narinder K. Chawla , Michael B. Thornton , Danniel B. Nguyen , Yan Lu , Ameena R. Gandhi , Chandra S. Arvizu , Deborah A. Kallick , Mariah R. Baughn , Jayalaxmi Ramkumar , Catherine M. Tribouley , Ernestine A. Lee , Li Ding , Neil Burford , Monique G. Yao , Junming Yang , Jennifer A. Griffin
发明人： Preeti G. Lal , Richard C. Graul , April J.A. Hafalia , Narinder K. Chawla , Michael B. Thornton , Danniel B. Nguyen , Yan Lu , Ameena R. Gandhi , Chandra S. Arvizu , Deborah A. Kallick , Mariah R. Baughn , Jayalaxmi Ramkumar , Catherine M. Tribouley , Ernestine A. Lee , Li Ding , Neil Burford , Monique G. Yao , Junming Yang , Jennifer A. Griffin
IPC分类号： A61K39/395 , C07K14/00 , C07H21/00 , C12N1/21 , C12P21/00 , C07K16/00 , C07K1/14 , A61P35/00 , A61P25/00 , A61P9/00 , G01N33/00 , G01N33/68 , C12Q1/68 , A61K38/16 , G01N33/53
CPC分类号： C07K14/705 , A61K38/00 , G01N2333/4719 , Y10T436/143333
摘要： The invention provides human G-protein coupled receptors (GCREC) and polynucleotides which identify and encode GCREC. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of GCREC.
摘要翻译： 本发明提供鉴定和编码GCREC的人G-蛋白偶联受体（GCREC）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供用于诊断，治疗或预防与GCREC异常表达相关的疾病的方法。
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公开(公告)号：US20070134680A1
公开(公告)日：2007-06-14
申请号：US11377409
申请日：2006-03-17
申请人： Y. Tang , Yalda Azimzai , Debopriya Das , Michael Thornton , Dyung Lu , Catherine Tribouley , Henry Yue , Ameena Gandhi , Narinder Chawla , Farrah Khan , Yan Lu , Monique Yao , April Hafalia , Vicki Elliott , Chandra Arvizu , Preeti Lal , Jayalaxmi Ramkumar , Danniel Nguyen , Mariah Baughn
发明人： Y. Tang , Yalda Azimzai , Debopriya Das , Michael Thornton , Dyung Lu , Catherine Tribouley , Henry Yue , Ameena Gandhi , Narinder Chawla , Farrah Khan , Yan Lu , Monique Yao , April Hafalia , Vicki Elliott , Chandra Arvizu , Preeti Lal , Jayalaxmi Ramkumar , Danniel Nguyen , Mariah Baughn
CPC分类号： C12Y301/01043 , A61K38/00 , C07H21/04 , C07K14/47 , C12N9/20
摘要： The invention provides human lipid metabolism molecules (LMM) and polynucleotides which identify and encode LMM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of LMM.
摘要翻译： 本发明提供了人类脂质代谢分子（LMM）和识别和编码LMM的多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供用于诊断，治疗或预防与LMM的异常表达相关的障碍的方法。
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公开(公告)号：US20070124581A1
公开(公告)日：2007-05-31
申请号：US10513957
申请日：2003-05-06
申请人： Reena Khare , Vicki Elliott , Joseph Marquis , Jayalaxmi Ramkumar , Narinder Chawla , Patricia Mason , April Hafalia , Anita Swarnakar , Pei Jin , Shanya Becha , Amy Kable , Uyen Tran , Mariah Baughn , Neil Burford , Richard Graul , Brooke Emerling , William Sprague , Jennifer Griffin , Craig Ison
发明人： Reena Khare , Vicki Elliott , Joseph Marquis , Jayalaxmi Ramkumar , Narinder Chawla , Patricia Mason , April Hafalia , Anita Swarnakar , Pei Jin , Shanya Becha , Amy Kable , Uyen Tran , Mariah Baughn , Neil Burford , Richard Graul , Brooke Emerling , William Sprague , Jennifer Griffin , Craig Ison
IPC分类号： H04L9/00
CPC分类号： C07K14/47 , A61K48/00 , G01N33/5014 , G01N2500/04
摘要： Various embodiments of the invention provide human cell adhesion and extracellular matrix proteins (CADECM) and polynucleotides which identify and encode CADECM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CADECM.
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公开(公告)号：US20050202478A1
公开(公告)日：2005-09-15
申请号：US11048068
申请日：2005-02-02
申请人： Michael Thornton , Li Ding , Chandra Arvizu , Monique Yao , Catherine Tribouley , Preeti Lal , April Hafalia , Mariah Baughn , Jayalaxmi Ramkumar , Yan Lu , Narinder Chawla
发明人： Michael Thornton , Li Ding , Chandra Arvizu , Monique Yao , Catherine Tribouley , Preeti Lal , April Hafalia , Mariah Baughn , Jayalaxmi Ramkumar , Yan Lu , Narinder Chawla
摘要： The invention provides human phosphodiesterases (HPDE) and polynucleotides which identify and encode HPDE. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of HPDE.
摘要翻译： 本发明提供了人类磷酸二酯酶（HPDE）和识别和编码HPDE的多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供用于诊断，治疗或预防与HPDE异常表达相关的疾病的方法。
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公开(公告)号：US20050123912A1
公开(公告)日：2005-06-09
申请号：US10486977
申请日：2002-08-14
申请人： Ines Barroso , Mariah Baughn , Shanya Becha , Julie Blake , Mark Borowsky , Neil Burford , Brendan Duggan , Vicki Elliott , Brooke Emerling , Ian Forsythe , Kimberly Gietzen , Ann Gorvad , Jennifer Griffin , April Hafalia , Cynthia Honchell , Craig Ison , Farrah Khan , Preeti Lal , Ernestine Lee , Sally Lee , Soo Lee , Joana Li , Dyung Lu , Yan Lu , Patricia Lehr-Mason , Danniel Nguyen , Jayalaxmi Ramkumar , William Sprague , Y Tang , Kavitha Thangavelu , Michael Thornton , Uyen Tran , Narinder Chawla , Bridget Warren , Yuming Xu , Monique Yao , Henry Yue , Huibin Yue , Yeganeh Zebarjadian
发明人： Ines Barroso , Mariah Baughn , Shanya Becha , Julie Blake , Mark Borowsky , Neil Burford , Brendan Duggan , Vicki Elliott , Brooke Emerling , Ian Forsythe , Kimberly Gietzen , Ann Gorvad , Jennifer Griffin , April Hafalia , Cynthia Honchell , Craig Ison , Farrah Khan , Preeti Lal , Ernestine Lee , Sally Lee , Soo Lee , Joana Li , Dyung Lu , Yan Lu , Patricia Lehr-Mason , Danniel Nguyen , Jayalaxmi Ramkumar , William Sprague , Y Tang , Kavitha Thangavelu , Michael Thornton , Uyen Tran , Narinder Chawla , Bridget Warren , Yuming Xu , Monique Yao , Henry Yue , Huibin Yue , Yeganeh Zebarjadian
IPC分类号： G01N33/50 , A61K38/00 , A61K45/00 , A61K49/00 , A61P1/00 , A61P1/16 , A61P3/10 , A61P7/00 , A61P9/00 , A61P9/10 , A61P11/00 , A61P11/06 , A61P13/00 , A61P15/00 , A61P17/00 , A61P17/06 , A61P19/00 , A61P19/02 , A61P19/06 , A61P19/10 , A61P21/00 , A61P25/00 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/28 , A61P27/02 , A61P29/00 , A61P31/04 , A61P31/10 , A61P31/12 , A61P31/18 , A61P33/00 , A61P35/00 , A61P37/02 , A61P37/08 , A61P43/00 , C07K14/47 , C07K16/18 , C12M1/00 , C12M1/34 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/02 , C12N15/09 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N37/00 , C07H21/04 , C12N9/22
CPC分类号： C07K14/4702 , A61K38/00 , G01N2500/00
摘要： Various embodiments of the invention provide human nucleic acid-associated proteins (NAAP) and polynucleotides which identify and encode NAAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NAAP.
摘要翻译： 本发明的各种实施方案提供了识别和编码NAAP的人核酸相关蛋白（NAAP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与NAAP异常表达相关的紊乱的方法。
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