公开(公告)号：US20030088093A1

公开(公告)日：2003-05-08

申请号：US10285571

申请日：2002-11-01

Applicant: National Inst. of Advanced Ind. Science and Tech.

Inventor： Osamu Sato ,  Kiyotaka Hatakeda ,  Yutaka Ikushima ,  Kazuo Torii

IPC: C07D201/04 ,  C07D211/36

CPC classification number: C07D201/04 ,  Y02P20/582

Abstract: A method for producing a lactam by using an organic solvent as a substrate solution, which makes it possible to introduce a high-concentration oxime into flowing high-temperature and high-pressure water, thereby allowing the high-concentration lactam to be synthesized with a high efficiency. With this method, the lactam is continuously synthesized at a high rate from the oxime under high-temperature and high-pressure water mixture conditions within a temperature range of no less than 250null C. and a pressure range of no less than 15 MPa.

Abstract translation: 通过使用有机溶剂作为底物溶液制备内酰胺的方法，可以将高浓度肟引入流动的高温高压水中，从而使高浓度的内酰胺与 高效率。 通过该方法，在不低于250℃的温度范围和不低于15MPa的压力范围内，在高温和高压水混合条件下，从肟连续合成内酰胺。