公开(公告)号：US20130323750A1

公开(公告)日：2013-12-05

申请号：US13903972

申请日：2013-05-28

申请人： National Taiwan University Hospital.

发明人： Kuan-Tun Wu ,  Ann Chen ,  Shuk-Man Ka

IPC分类号： G01N33/68

CPC分类号： G01N33/6872 ,  G01N33/68 ,  G01N2333/902 ,  G01N2800/347

摘要： A method for analyzing apoptosis inducing factor-2 (AIF-2) is disclosed, which has not been found in urine samples of human patients with chronic kidney disease, to establish AIF-2 as a non-invasive biomarker for chronic kidney disease. The method includes: collecting a plurality of urine samples; conducting western blot for each urine sample for detecting the AIF-2 protein content in each urine sample; and conducting statistical analysis of the AIF-2 protein content in each urine sample to establish AIF-2 as a biological marker for chronic kidney disease.

摘要翻译： 公开了一种分析凋亡诱导因子-2（AIF-2）的方法，其在慢性肾脏疾病患者的尿液样本中尚未发现，以建立AIF-2作为慢性肾脏疾病的非侵入性生物标志物。 该方法包括：收集多个尿样; 对每个尿样进行蛋白印迹检测，以检测每个尿样中的AIF-2蛋白含量; 并对每个尿液样品中的AIF-2蛋白质含量进行统计分析，建立AIF-2作为慢性肾脏疾病的生物学标志物。