公开(公告)号：US06261543B1

公开(公告)日：2001-07-17

申请号：US09416104

申请日：1999-10-12

申请人： Neil Robert Fletcher ,  Miyuki Kanda ,  Howard Allen Ketelson ,  Graham Andrew Turner

发明人： Neil Robert Fletcher ,  Miyuki Kanda ,  Howard Allen Ketelson ,  Graham Andrew Turner

IPC分类号： A61K732

CPC分类号： A61Q15/00 ,  A61K8/26 ,  A61K8/28 ,  A61K8/31 ,  A61K8/585 ,  A61K8/732 ,  A61K8/92

摘要： Antiperspirant emulsions which exhibit excellent phase stability even in the presence of an effective concentration of antiperspirant salts in solution and which are thickened are obtainable by dispersing a hydratable polymer and particularly an amphoteric or cationic modified starch in an aqueous emulsion forming a viscous emulsion, often at an elevated temperature, subjecting the emulsion to high shear, thereby reducing the droplet size of the dispersed oil phase, bringing the emulsion to below 40° C. and introducing the antiperspirant, preferably in aqueous solution. The viscous emulsion subjected to high shear mixing desirably has a Sheer Stress of 10 to 500 Pa. The resultant emulsions show good phase stability even when they contain aluminium/ zirconium antiperspirant salts that promote instability and even at elevated storage temperatures such as at 50° C.

摘要翻译： 即使在溶液中存在有效浓度的止汗盐并且增稠的情况下也显示出优异的相稳定性的止汗剂乳液可以通过将可水合的聚合物，特别是两性或阳离子改性淀粉分散在形成粘性乳液的水性乳液中，通常在 升高的温度，对乳液进行高剪切，从而降低分散油相的液滴尺寸，使乳液低于40℃，并且优选在水溶液中引入止汗剂。 进行高剪切混合的粘性乳液理想地具有10至500Pa的剪切应力。所得到的乳液即使当它们含有促进不稳定性的甚至在升高的储存温度（例如50℃）时也显示出良好的相稳定性 。