公开(公告)号：US20130199942A1

公开(公告)日：2013-08-08

申请号：US13367648

申请日：2012-02-07

申请人： Neil WHITEHEAD ,  Stuart Phillips ,  David Morris ,  Joanne McIlrath ,  Robert MacLeod ,  Lynsey Whyte ,  Karn Campbell ,  Ramsay Darling ,  James McLaren ,  Russell Bain

发明人： Neil WHITEHEAD ,  Stuart Phillips ,  David Morris ,  Joanne McIlrath ,  Robert MacLeod ,  Lynsey Whyte ,  Karn Campbell ,  Ramsay Darling ,  James McLaren ,  Russell Bain

IPC分类号： G01N27/327 ,  G01N33/66

CPC分类号： C12Q1/001 ,  C12Q1/006

摘要： An electrochemical-based analytical test strip (“EBAT”) for the determination of an analyte in a bodily fluid sample includes an electrically insulating substrate layer with a distal end and a patterned conductor layer that is disposed over the electrically-insulating substrate layer and has a working electrode (“WE”) and a counter/reference electrode (“C/RE”). The EBAT also includes a patterned insulation layer with an electrode exposure window configured to expose a WE exposed portion and a C/RE exposed portion, an enzymatic reagent layer; and a patterned spacer layer. The patterned insulation layer and the patterned spacer layer define a sample receiving chamber with a sample-receiving opening (“SRO”) at the distal end of the electrically insulating substrate layer and that extends across the WE exposed portion and the C/RE exposed portion. Furthermore, the enzymatic reagent layer is disposed over the WE and C/RE exposed portions and extends no more than 400 μm toward the SRO.

摘要翻译： 用于测定体液样品中的分析物的基于电化学的分析测试条（“EBAT”）包括具有远端的电绝缘基底层和设置在电绝缘基底层上的图案化导体层，并且具有 工作电极（“WE”）和计数器/参考电极（“C / RE”）。 EBAT还包括具有电极曝光窗口的图案化绝缘层，其被配置为暴露WE暴露部分和C / RE暴露部分，即酶试剂层; 和图案化间隔层。 图案化绝缘层和图案化间隔层限定了在电绝缘基底层的远端处具有样品接收开口（“SRO”）的样品接收室，并且延伸穿过WE暴露部分和C / RE暴露部分 。 此外，酶试剂层设置在WE和C / RE暴露部分上方，朝向SRO延伸不超过400μm。