公开(公告)号：US20190023772A1

公开(公告)日：2019-01-24

申请号：US15874102

申请日：2018-01-18

Applicant: Nestec SA

Inventor： Timothy James Wooster ,  Ebenezer Satyaraj ,  Eddy Gombas ,  Beat Gerber

IPC: C07K16/18 ,  A61K47/42 ,  A61K47/36

Abstract: Compositions and methods reduce symptoms of human allergy to cats. The effectiveness of a molecule which specifically binds to Feline domesticus allergen number 1 (Fel D1) is enhanced by prolonging the time the immunoglobulin stays within the mouth of a cat to whom the anti-Fel D1 molecule is administered in a pet food. The compositions and methods use a powder that is a dried hydrogel encapsulating the anti-Fel D1 molecule, and the hydrogel is based on gelatin, collagen peptides, or gelatin and collagen peptides; and carrageenan. The methods of making the powder provide a high encapsulation efficacy, sustained release of the anti-Fel D1 molecule in the cat's mouth, and oral adhesion of the anti-Fel D1 molecule in the cat's mouth.