专利检索 ap:("NeuroTrauma Sciences LLC") AND inv:"Natalie KELK" 第 1 页

1.

发明公开
SALTS AND CRYSTALLINE FORMS OF (3E) 3-[O-[(PHOSPHONOOXY)METHYL]OXIME]-PREGN-4-ENE-3,20-DIONE AND RELATED USES 审中-公开

公开(公告)号：US20240247026A1

公开(公告)日：2024-07-25

申请号：US18555707

申请日：2022-04-19

申请人： NeuroTrauma Sciences LLC

发明人： Raymond Brent MILLER , Natalie KELK , David PEARSON , Gideon SHAPIRO

IPC分类号： C07J51/00 , A61K31/661

CPC分类号： C07J51/00 , A61K31/661

摘要： The present disclosure relates to a crystalline form of (((((E)-1-((8S,9S,10R, 13S,14S,17S)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethylidene)amino)oxy)methyl dihydrogen phosphate), and pharmaceutically acceptable salts thereof, which may be useful in methods of treatment of the human or animal body. The present disclosure also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them and to their use in the treatment of disorders, such as managing inflammation (e.g., inflammation resulting from traumatic brain injury or stroke).