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公开(公告)号：US20230304241A1
公开(公告)日：2023-09-28
申请号：US17704940
申请日：2022-03-25
Applicant: Nicholas Moore
Inventor： Nicholas Moore
CPC classification number: E01H3/02 , B05B1/205 , B05B13/005 , B05B13/0415 , B08B3/024
Abstract: The present invention provides a curb cleaning system having a main body configured in an L shape, an adjustable arm attached to the main body, a guide wheel attached to said adjustable arm, at least two solution nozzles each positioned on complimentary surfaces of said L shape, and a wand attached to the adjustable arm.
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Patent Agency Ranking
2.发明申请Therapeutic Uses Of Compounds Having Combined SERT, 5-HT3 And 5-HT1A Activity 有权具有SERT，5-HT3和5-HT1A活性的化合物的治疗用途公开(公告)号：US20110201617A1
公开(公告)日：2011-08-18
申请号：US12741780
申请日：2008-11-12
Applicant: Nicholas Moore , Marianne Dragheim , Aneil Batra , Jin Chon
Inventor： Nicholas Moore , Marianne Dragheim , Aneil Batra , Jin Chon
IPC: A61K31/495 , A61P25/18 , A61P25/24 , A61P25/28 , A61P25/22
CPC classification number: A61K31/495
Abstract: New pharmaceutical uses of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine and pharmaceutically acceptable salts thereof are provided.
Abstract translation: 提供1- [2-（2,4-二甲基苯基硫烷基）苯基]哌嗪及其药学上可接受的盐的新药用途。
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![1-[2-(2,4-dimethylphenylsulfanyl)-phenyl] piperazine as a compound with combined serotonin reuptake, 5-HT3 and 5-HT1A activity for the treatment of cognitive impairment](/abs-image/US/2014/05/13/US08722684B2/abs.jpg.150x150.jpg)
3.发明授权1-[2-(2,4-dimethylphenylsulfanyl)-phenyl] piperazine as a compound with combined serotonin reuptake, 5-HT3 and 5-HT1A activity for the treatment of cognitive impairment 有权1- [2-（2,4-二甲基苯基硫烷基） - 苯基]哌嗪作为具有组合的5-羟色胺再摄取的化合物，用于治疗认知障碍的5-HT3和5-HT1A活性公开(公告)号：US08722684B2
公开(公告)日：2014-05-13
申请号：US12301061
申请日：2007-06-15
Applicant: Benny Bang-Andersen , Andre Faldt , Arne Mork , Heidi Lopez de Diego , Rene Holm , Tine Bryan Stensbol , Nicholas Moore
Inventor： Benny Bang-Andersen , Andre Faldt , Arne Mork , Heidi Lopez de Diego , Rene Holm , Tine Bryan Stensbol , Nicholas Moore
IPC: A61K31/495 , C07D295/096 , A61K9/16 , A61K9/20
CPC classification number: A61K31/495 , A61K9/14 , C07D295/096 , Y10T428/2982
Abstract: 1-[2-(2,4-dimethylphenylsulphanyl)phenyl]piperazine exhibits potent activity on SERT, 5-HT3 and 5-HT1A and may as such be useful for the treatment of cognitive impairment, especially in depressed patients.
Abstract translation: 1- [2-（2,4-二甲基苯基硫烷基）苯基]哌嗪显示出对SERT，5-HT3和5-HT1A的有效活性，并且可以用于治疗认知障碍，特别是抑郁症患者。
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![1- [2-(2,4-DIMETHYLPHENYLSULFANYL)-PHENYL] PIPERAZINE AS A COMPOUND WITH COMBINED SEROTONIN REUPTAKE, 5-HT3 AND 5-HT1A ACTIVITY FOR THE TREATMENT OF PAIN OR RESIDUAL SYMPTOMS IN DEPRESSION RELATING TO SLEEP AND COGNITION](/abs-image/US/2011/01/13/US20110009422A1/abs.jpg.150x150.jpg)
4.发明申请1- [2-(2,4-DIMETHYLPHENYLSULFANYL)-PHENYL] PIPERAZINE AS A COMPOUND WITH COMBINED SEROTONIN REUPTAKE, 5-HT3 AND 5-HT1A ACTIVITY FOR THE TREATMENT OF PAIN OR RESIDUAL SYMPTOMS IN DEPRESSION RELATING TO SLEEP AND COGNITION 有权1- [2-（2,4-二甲基苯基） - 苯基]哌嗪作为具有组合的丝氨酸反应，5-HT3和5-HT1A活性的化合物，用于治疗与睡眠和认知相关的疼痛或残留症状公开(公告)号：US20110009422A1
公开(公告)日：2011-01-13
申请号：US12527911
申请日：2008-03-14
Applicant: Nicholas Moore , Tine Bryan Stensbol
Inventor： Nicholas Moore , Tine Bryan Stensbol
IPC: A61K31/495 , A61P25/24 , A61P29/00
CPC classification number: A61K31/495 , C07D295/096
Abstract: The use of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine in the treatment of pain and residual symptoms in depression is provided.
Abstract translation: 提供1- [2-（2,4-二甲基苯基硫烷基）苯基]哌嗪用于治疗抑郁症中的疼痛和残留症状。
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![1- [2- (2,4-DIMETHYLPHENYLSULFANYL)-PHENYL] PIPERAZINE AS A COMPOUND WITH COMBINED SEROTONIN REUPTAKE, 5-HT3 AND 5-HT1A ACTIVITY FOR THE TREATMENT OF COGNITIVE IMPAIRMENT](/abs-image/US/2010/11/25/US20100297240A1/abs.jpg.150x150.jpg)
5.发明申请1- [2- (2,4-DIMETHYLPHENYLSULFANYL)-PHENYL] PIPERAZINE AS A COMPOUND WITH COMBINED SEROTONIN REUPTAKE, 5-HT3 AND 5-HT1A ACTIVITY FOR THE TREATMENT OF COGNITIVE IMPAIRMENT 有权1- [2-（2,4-二甲基苯基） - 苯基]哌嗪作为具有组合丝氨酸反应的化合物，5-HT3和5-HT1A活性用于治疗认知损伤公开(公告)号：US20100297240A1
公开(公告)日：2010-11-25
申请号：US12301061
申请日：2007-06-15
Applicant: Benny Bang-Andersen , Andre Faldt , Arne Mork , Heidi Lopez De Diego , Rene Holm , Tine Bryan Stensbol , Lone Munch Ringgaard , Michael J. Mealy , Michael Harold Rock , Jorgen Brodersen , Morten Jorgensen , Nicholas Moore
Inventor： Benny Bang-Andersen , Andre Faldt , Arne Mork , Heidi Lopez De Diego , Rene Holm , Tine Bryan Stensbol , Lone Munch Ringgaard , Michael J. Mealy , Michael Harold Rock , Jorgen Brodersen , Morten Jorgensen , Nicholas Moore
IPC: A61K31/495 , C07D295/096 , A61P25/24 , A61P25/28 , A61P35/00 , A61P25/16 , A61P25/32 , A61P25/22 , A61P25/18 , A61K9/14
CPC classification number: A61K31/495 , A61K9/14 , C07D295/096 , Y10T428/2982
Abstract: 1-[2-(2,4-dimethylphenylsulphanyl)phenyl]piperazine exhibits potent activity on SERT, 5-HT3 and 5-HT1A and may as such be useful for the treatment of cognitive impairment, especially in depressed patients.
Abstract translation: 1- [2-（2,4-二甲基苯基硫烷基）苯基]哌嗪显示出对SERT，5-HT3和5-HT1A的有效活性，并且可以用于治疗认知障碍，特别是抑郁症患者。
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![1-[2-(2,4-dimethylphenylsulfanyl)-phenyl] piperazine as a compound with combined serotonin reuptake, 5-HT3 and 5-HT1A activity for the treatment of pain or residual symptoms in depression relating to sleep and cognition](/abs-image/US/2014/03/04/US08664225B2/abs.jpg.150x150.jpg)
6.发明授权1-[2-(2,4-dimethylphenylsulfanyl)-phenyl] piperazine as a compound with combined serotonin reuptake, 5-HT3 and 5-HT1A activity for the treatment of pain or residual symptoms in depression relating to sleep and cognition 有权1- [2-（2,4-二甲基苯基硫烷基） - 苯基]哌嗪作为具有组合的5-羟色胺再摄取，5-HT3和5-HT1A活性的化合物，用于治疗与睡眠和认知相关的抑郁症中的疼痛或残留症状公开(公告)号：US08664225B2
公开(公告)日：2014-03-04
申请号：US12527911
申请日：2008-03-14
Applicant: Nicholas Moore , Tine Bryan Stensbol
Inventor： Nicholas Moore , Tine Bryan Stensbol
IPC: A61K31/4965
CPC classification number: A61K31/495 , C07D295/096
Abstract: The use of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine in the treatment of pain and residual symptoms in depression is provided.
Abstract translation: 提供1- [2-（2,4-二甲基苯基硫烷基）苯基]哌嗪用于治疗抑郁症中的疼痛和残留症状。
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