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公开(公告)号:US20130171240A1
公开(公告)日:2013-07-04
申请号:US13786883
申请日:2013-03-06
发明人: Yoshiro Niitsu , Junji Kato , Yasushi Sato , Joseph E Payne , John A Gaudette , Zheng Hou , Victor Knopov , Richard P Witte , Mohammad Ahmadian , Loren A Perelman , Yasunobu Tanaka , Violetta Akopian
IPC分类号: A61K47/18 , A61K31/713 , A61K47/24 , A61K9/127
CPC分类号: A61K47/183 , A61K9/0019 , A61K9/127 , A61K31/07 , A61K31/7088 , A61K31/713 , A61K45/06 , A61K47/18 , A61K47/24 , Y10S514/893 , A61K2300/00
摘要: Disclosed is a stellate cell-specific drug carrier comprising a stellate cell-specific amount of a retinoid derivative and/or a vitamin A analogue, and a drug carrier component other than the retinoid derivative and/or a vitamin A analogue. Also disclosed in a medicine comprising the stellate cell-specific drug carrier, and a drug in an amount effective for controlling the activity or growth of stellate cells.
摘要翻译: 公开了一种星状细胞特异性药物载体,其包含星状细胞特异性量的类视色素衍生物和/或维生素A类似物,以及除类视黄醇衍生物和/或维生素A类似物以外的药物载体成分。 还包括星状细胞特异性药物载体的药物和有效控制星状细胞活性或生长的药物。
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公开(公告)号:US20160015656A2
公开(公告)日:2016-01-21
申请号:US13789032
申请日:2013-03-07
发明人: Yoshiro Niitsu , Akihiro Yoneda , Hirotoshi Ishiwatari , Joseph E Payne , John A Gaudette , Zheng Hou , Victor Knopov , Richard P Witte , Mohammad Ahmadian , Loren A Perelman , Yasunobu Tanaka , Violetta Akopian
CPC分类号: A61K31/07 , A61K31/203 , A61K38/05 , A61K38/4886 , A61K45/00 , A61K45/06 , A61K47/551 , A61K47/60 , C07C2601/16 , C07F9/106 , A61K2300/00
摘要: The present invention relates to a pharmaceutical composition and a method for regenerating normal tissue from fibrotic tissue, the pharmaceutical composition and the method employing a collagen-reducing substance. In accordance with the present invention, normal tissue can be therapeutically regenerated from fibrotic tissue.
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