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公开(公告)号：US20220062253A1
公开(公告)日：2022-03-03
申请号：US17446063
申请日：2021-08-26
发明人： Brijeshkumar B. Pandya , Govind R. Jagadale , Dasaradhi Lakkaraju , Bala Tripura Sundari Chodavarapu , Anand Shukla , Jwalant Shukla
IPC分类号： A61K31/4439 , A61K9/16 , A61J1/10
摘要： A spray-dried storage stable pantoprazole composition is provided. The pantoprazole composition includes a pantoprazole and an excipient matrix including sodium chloride (NaCl). The pantoprazole is substantially uniformly dispersed in the excipient matrix. A method for forming a storage stable pantoprazole composition is also provided. The method includes combining a bulking agent and water to form a first solution, combining a pantoprazole and the first solution to form a second solution, combining sodium hydroxide and the second solution to form a bulk solution, and removing water from the bulk solution by drying to form the storage stable pantoprazole composition.
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公开(公告)号：US11813291B2
公开(公告)日：2023-11-14
申请号：US17499001
申请日：2021-10-12
发明人： Brijeshkumar B. Pandya , Govind R. Jagadale , Dasaradhi Lakkaraju , Bala Tripura Sundari Chodavarapu , Anand Shukla , Jwalant Shukla
CPC分类号： A61K33/42 , A61K9/08 , A61M5/168 , A61M39/0208
摘要： A ready-to-use (RTU) potassium phosphates in sodium chloride solution for phosphorus replacement therapy includes potassium phosphate and sodium chloride at a fixed volume with 15 mmol/100 mL phosphorus and 22 mEq/100 mL potassium and less than 50 mcg/L aluminum.
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公开(公告)号：US20220110969A1
公开(公告)日：2022-04-14
申请号：US17499001
申请日：2021-10-12
发明人： Brijeshkumar B. Pandya , Govind R. Jagadale , Dasaradhi Lakkaraju , Bala Tripura Sundari Chodavarapu , Anand Shukla , Jwalant Shukla
摘要： A ready-to-use (RTU) potassium phosphates in sodium chloride solution for phosphorus replacement therapy includes potassium phosphate and sodium chloride at a fixed volume with 15 mmol/100 mL phosphorus and 22 mEq/100 mL potassium and less than 50 mcg/L aluminum.
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公开(公告)号：US12102624B2
公开(公告)日：2024-10-01
申请号：US17446063
申请日：2021-08-26
发明人： Brijeshkumar B. Pandya , Govind R. Jagadale , Dasaradhi Lakkaraju , Bala Tripura Sundari Chodavarapu , Anand Shukla , Jwalant Shukla
IPC分类号： A61K31/4439 , A61J1/10 , A61K9/16
CPC分类号： A61K31/4439 , A61J1/10 , A61K9/1611 , A61K9/1694
摘要： A spray-dried storage stable pantoprazole composition is provided. The pantoprazole composition includes a pantoprazole and an excipient matrix including sodium chloride (NaCl). The pantoprazole is substantially uniformly dispersed in the excipient matrix. A method for forming a storage stable pantoprazole composition is also provided. The method includes combining a bulking agent and water to form a first solution, combining a pantoprazole and the first solution to form a second solution, combining sodium hydroxide and the second solution to form a bulk solution, and removing water from the bulk solution by drying to form the storage stable pantoprazole composition.
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公开(公告)号：US11925661B2
公开(公告)日：2024-03-12
申请号：US18460941
申请日：2023-09-05
发明人： Brijeshkumar B. Pandya , Govind R. Jagadale , Dasaradhi Lakkaraju , Bala Tripura Sundari Chodavarapu , Anand Shukla , Jwalant Shukla
摘要： Ready-to-use (RTU) potassium phosphates solutions for phosphorus replacement therapy are presented that include potassium phosphate and sodium chloride at a fixed volume with 1.5 to 15 mmol/100 mL phosphorus, no more than 22 mEq/100 mL potassium and less than 50 mcg/L aluminum.
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公开(公告)号：US20230405045A1
公开(公告)日：2023-12-21
申请号：US18460941
申请日：2023-09-05
发明人： Brijeshkumar B. Pandya , Govind R. Jagadale , Dasaradhi Lakkaraju , Bala Tripura Sundari Chodavarapu , Anand Shukla , Jwalant Shukla
摘要： Ready-to-use (RTU) potassium phosphates solutions for phosphorus replacement therapy are presented that include potassium phosphate and sodium chloride at a fixed volume with 1.5 to 15 mmol/100 mL phosphorus, no more than 22 mEq/100 mL potassium and less than 50 mcg/L aluminum.
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