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公开(公告)号：US20220354794A1
公开(公告)日：2022-11-10
申请号：US17854914
申请日：2022-06-30
发明人： Bala Tripura Sundari Chodavarapu , Thirupathi Mangali , Jay Shukla , Anand Shukla , Dasaradhi Lakkaraju
IPC分类号： A61K9/19 , A61K31/515 , A61K47/02
摘要： A composition of, method for producing, and use of an amorphous lyophilized Phenobarbital Sodium having high purity are presented. The amorphous lyophilized Phenobarbital Sodium is storage-stable being essentially void of impurities (e.g., phenyl ethylacetylurea (PEAU), 2-ethyl-2-phenylmalonamide (2EPMM), and/or alpha-phenylbutyrylguanidine (PBG)) upon reconstitution in water.
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公开(公告)号：US20210085608A1
公开(公告)日：2021-03-25
申请号：US17025881
申请日：2020-09-18
发明人： Bala Tripura Sundari Chodavarapu , Thirupathi Mangali , Jay Shukla , Anand Shukla , Dasaradhi Lakkaraju
IPC分类号： A61K9/19 , A61K9/00 , A61K31/515
摘要： A composition of, method for producing, and use of an amorphous lyophilized Phenobarbital Sodium having high purity are presented. The amorphous lyophilized Phenobarbital Sodium is storage-stable being essentially void of impurities (e.g., phenylethylacetylurea (PEAU), 2-ethyl-2-phenylmalonamide (2EPMM), and/or alpha-phenylbutyrylguanidine (PBG)) upon reconstitution in water.
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公开(公告)号：US11813291B2
公开(公告)日：2023-11-14
申请号：US17499001
申请日：2021-10-12
发明人： Brijeshkumar B. Pandya , Govind R. Jagadale , Dasaradhi Lakkaraju , Bala Tripura Sundari Chodavarapu , Anand Shukla , Jwalant Shukla
CPC分类号： A61K33/42 , A61K9/08 , A61M5/168 , A61M39/0208
摘要： A ready-to-use (RTU) potassium phosphates in sodium chloride solution for phosphorus replacement therapy includes potassium phosphate and sodium chloride at a fixed volume with 15 mmol/100 mL phosphorus and 22 mEq/100 mL potassium and less than 50 mcg/L aluminum.
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公开(公告)号：US11406598B2
公开(公告)日：2022-08-09
申请号：US17025881
申请日：2020-09-18
发明人： Bala Tripura Sundari Chodavarapu , Thirupathi Mangali , Jay Shukla , Anand Shukla , Dasaradhi Lakkaraju
IPC分类号： A61K9/19 , A61K31/515 , A61K9/00
摘要： A composition of, method for producing, and use of an amorphous lyophilized Phenobarbital Sodium having high purity are presented. The amorphous lyophilized Phenobarbital Sodium is storage-stable being essentially void of impurities (e.g., phenylethylacetylurea (PEAU), 2-ethyl-2-phenylmalonamide (2EPMM), and/or alpha-phenylbutyrylguanidine (PBG)) upon reconstitution in water.
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公开(公告)号：US20230043597A1
公开(公告)日：2023-02-09
申请号：US17871058
申请日：2022-07-22
发明人： Thirupathi Mangali , Bala Tripura Sundari Chodavarapu , Anand Shukla , Jay Shukla , Dasaradhi Lakkaraju
摘要： Described is an aqueous calcium gluconate solution formulated without calcium saccharate, which can be stored in a flexible plastic bag and can be terminally sterilized.
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公开(公告)号：US20220062253A1
公开(公告)日：2022-03-03
申请号：US17446063
申请日：2021-08-26
发明人： Brijeshkumar B. Pandya , Govind R. Jagadale , Dasaradhi Lakkaraju , Bala Tripura Sundari Chodavarapu , Anand Shukla , Jwalant Shukla
IPC分类号： A61K31/4439 , A61K9/16 , A61J1/10
摘要： A spray-dried storage stable pantoprazole composition is provided. The pantoprazole composition includes a pantoprazole and an excipient matrix including sodium chloride (NaCl). The pantoprazole is substantially uniformly dispersed in the excipient matrix. A method for forming a storage stable pantoprazole composition is also provided. The method includes combining a bulking agent and water to form a first solution, combining a pantoprazole and the first solution to form a second solution, combining sodium hydroxide and the second solution to form a bulk solution, and removing water from the bulk solution by drying to form the storage stable pantoprazole composition.
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公开(公告)号：US20210369673A1
公开(公告)日：2021-12-02
申请号：US17331011
申请日：2021-05-26
发明人： Govind R. Jagadale , Dasaradhi Lakkaraju , Bala Tripura Sundari Chodavarapu , Niravkumar Prajapati , Anand Shukla , Jay Shukla
IPC分类号： A61K31/4035 , A61K47/24 , A61K47/26 , A61K47/14 , A61K47/38
摘要： Compositions of a stabilized chlorthalidone suspension and methods for making a stabilized chlorthalidone suspension include chlorthalidone along with a solubilizing and/or wetting agent, a suspending agent, and a viscosity increasing agent and/or an anti-caking agent, wherein the stabilized chlorthalidone suspension is a uniform dispersion with consistent concentration of chlorthalidone throughout the composition and storage.
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公开(公告)号：US11957658B2
公开(公告)日：2024-04-16
申请号：US17331011
申请日：2021-05-26
发明人： Govind R. Jagadale , Dasaradhi Lakkaraju , Bala Tripura Sundari Chodavarapu , Niravkumar Prajapati , Anand Shukla , Jay Shukla
IPC分类号： A61K31/4035 , A61K47/14 , A61K47/24 , A61K47/26 , A61K47/38
CPC分类号： A61K31/4035 , A61K47/14 , A61K47/24 , A61K47/26 , A61K47/38
摘要： Compositions of a stabilized chlorthalidone suspension and methods for making a stabilized chlorthalidone suspension include chlorthalidone along with a solubilizing and/or wetting agent, a suspending agent, and a viscosity increasing agent and/or an anti-caking agent, wherein the stabilized chlorthalidone suspension is a uniform dispersion with consistent concentration of chlorthalidone throughout the composition and storage.
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公开(公告)号：US11878076B2
公开(公告)日：2024-01-23
申请号：US18100804
申请日：2023-01-24
发明人： Bala Tripura Sundari Chodavarapu , Thirupathi Mangali , Jay Shukla , Anand Shukla , Dasaradhi Lakkaraju
IPC分类号： A61K9/19 , A61K47/02 , A61K31/515
CPC分类号： A61K9/19 , A61K31/515 , A61K47/02
摘要： A composition of, method for producing, and use of an amorphous lyophilized Phenobarbital Sodium having high purity are presented. The amorphous lyophilized Phenobarbital Sodium is storage-stable being essentially void of impurities (e.g., phenylethylacetylurea (PEAU), 2-ethyl-2-phenylmalonamide (2EPMM), and/or alpha-phenylbutyrylguanidine (PBG)) upon reconstitution in water.
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公开(公告)号：US20220110969A1
公开(公告)日：2022-04-14
申请号：US17499001
申请日：2021-10-12
发明人： Brijeshkumar B. Pandya , Govind R. Jagadale , Dasaradhi Lakkaraju , Bala Tripura Sundari Chodavarapu , Anand Shukla , Jwalant Shukla
摘要： A ready-to-use (RTU) potassium phosphates in sodium chloride solution for phosphorus replacement therapy includes potassium phosphate and sodium chloride at a fixed volume with 15 mmol/100 mL phosphorus and 22 mEq/100 mL potassium and less than 50 mcg/L aluminum.
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