公开(公告)号：US20240199591A1

公开(公告)日：2024-06-20

申请号：US18392203

申请日：2023-12-21

申请人： Northeastern University ,  Indiana University Research and Technology Corporation

发明人： Ganeshsingh A. THAKUR ,  Diomedes E. LOGOTHETIS ,  Lucas CANTWELL ,  Yu XU ,  Anantha SHEKHAR

IPC分类号： C07D409/12 ,  A61K31/415 ,  A61P25/22 ,  C07D231/40 ,  C07D401/12 ,  C07D403/12 ,  C07D405/12 ,  C07D413/12 ,  C07D417/12

CPC分类号： C07D409/12 ,  A61K31/415 ,  A61P25/22 ,  C07D231/40 ,  C07D401/12 ,  C07D403/12 ,  C07D405/12 ,  C07D413/12 ,  C07D417/12

摘要： Selective small molecule regulators of GIRK potassium channels are provided, which are effective in treatment of post-traumatic stress disorder and other medical conditions.

公开(公告)号：US20210253561A1

公开(公告)日：2021-08-19

申请号：US17053458

申请日：2019-06-11

申请人： Northeastern University ,  Indiana University Research and Technology Corporation

发明人： Ganeshingh A. THAKUR ,  Diomedes E. LOGOTHETIS ,  Lucas CANTWELL ,  Yu XU ,  Anantha SHEKAR

IPC分类号： C07D409/12 ,  C07D231/40 ,  C07D413/12 ,  C07D405/12 ,  C07D417/12 ,  C07D403/12 ,  C07D401/12 ,  A61P25/22

摘要： Selective small molecule regulators of GIRK potassium channels are provided, which are effective in treatment of post-traumatic stress disorder and other medical conditions.