公开(公告)号：USRE45173E1

公开(公告)日：2014-09-30

申请号：US13929901

申请日：2013-06-28

Applicant: Novartis AG

Inventor： Mark Gary Bock ,  Christoph Gaul ,  Venkateshwar Rao Gunmadi ,  Saumitra Sengupta

IPC: A61K31/415 ,  C07D233/00

CPC classification number: A61K31/4439 ,  A61K31/444 ,  A61K45/06 ,  C07D401/04 ,  C07D401/14 ,  C07D405/14 ,  C07D409/14 ,  C07D413/14 ,  C07D417/14 ,  C07D471/04 ,  C07D487/04 ,  C07D495/04

Abstract: The present invention provides compounds of Formula (I) and (II), or a pharmaceutically acceptable salts thereof, where R53, R54, p, q, and n are as defined herein. The compounds of the present invention have been found to be useful as 17α-hydroxylase/C17,20-lyase inhibitors.

Abstract translation: 本发明提供式（I）和（II）化合物或其药学上可接受的盐，其中R53，R54，p，q和n如本文所定义。 已经发现本发明的化合物可用作17α-羟化酶/ C17,20-裂解酶抑制剂。