公开(公告)号：US20250136685A1

公开(公告)日：2025-05-01

申请号：US18999104

申请日：2024-12-23

Applicant: Novartis AG

Inventor： Verena BRAND ,  Dominik FEUERBACH ,  Fabrizio GASPARINI ,  Nathalie GEORGE ,  Eveline SCHAADT ,  Derya SHIMSHEK ,  Honnappa SRINIVAS ,  Markus WALDHUBER ,  Rainer WILCKEN

IPC: C07K16/28 ,  A61K39/00 ,  A61K39/395 ,  A61P25/28 ,  C12N7/00 ,  C12N15/70

Abstract: The present invention provides antibodies that bind to and stabilize human Triggering Receptor Expressed on Myeloid cells 2 (TREM2) protein and methods of using these antibodies.

公开(公告)号：US20230167174A1

公开(公告)日：2023-06-01

申请号：US17934795

申请日：2022-09-23

Applicant: Novartis AG

Inventor： Verena BRAND ,  Dominik FEUERBACH ,  Fabrizio GASPARINI ,  Nathalie GEORGE ,  Eveline SCHAADT ,  Derya SHIMSHEK ,  Honnappa SRINIVAS ,  Markus WALDHUBER ,  Rainer WILCKEN

IPC: C07K16/28 ,  A61P25/28 ,  A61K39/395 ,  C12N7/00 ,  C12N15/70

CPC classification number: C07K16/2803 ,  A61K39/3955 ,  A61P25/28 ,  C12N7/00 ,  C12N15/70 ,  A61K2039/505

Abstract: The present invention provides antibodies that bind to and stabilize human Triggering Receptor Expressed on Myeloid cells 2 (TREM2) protein and methods of using these antibodies.