公开(公告)号：US20180028468A1

公开(公告)日：2018-02-01

申请号：US15583882

申请日：2017-05-01

申请人： OCUNEXUS THERAPEUTICS, INC.

发明人： David L. BECKER ,  Anthony R.J. PHILLIPS ,  Daniel J. GILMARTIN

IPC分类号： A61K9/70 ,  A61K31/713 ,  D06M15/507 ,  A61K47/42 ,  A61K47/36 ,  A61K47/34 ,  C12N15/113 ,  A61K9/00

CPC分类号： A61K9/7092 ,  A61K9/0014 ,  A61K31/713 ,  A61K47/34 ,  A61K47/36 ,  A61K47/42 ,  A61L15/44 ,  A61L15/64 ,  A61L2300/252 ,  A61L2300/412 ,  C12N15/113 ,  C12N15/1138 ,  C12N2310/11 ,  C12N2320/31 ,  C12N2320/32 ,  C12N2320/35 ,  D06M15/507 ,  D06M2101/14

摘要： Sustained release drug delivery devices including scaffolds comprising combinations of anti-connexin, anti-gap junction, anti-hemichannel and/or other agents, for example, anti-connexin 26 and anti-connexin 43 polynucleotides or peptidomimetics, uses therefor, and kits comprising sustained release scaffold.