公开(公告)号：US12234289B2

公开(公告)日：2025-02-25

申请号：US17311148

申请日：2019-12-06

Applicant: ONO PHARMACEUTICAL CO., LTD. ,  TOKUSHIMA UNIVERSITY

Inventor： Taku Okazaki ,  Daisuke Sugiura ,  Takeo Maeda ,  Shiro Shibayama

IPC: C07K16/28 ,  A61K39/00 ,  A61P37/06

Abstract: An immunosuppressive agent containing a substance that is selected from anti-CD80 antibodies and anti-PD-L1 antibodies and that promotes binding between PD-L1 and PD-1.

公开(公告)号：US20250145719A1

公开(公告)日：2025-05-08

申请号：US19017160

申请日：2025-01-10

Applicant: Ono Pharmaceutical Co., Ltd. ,  Tokushima University

Inventor： Taku OKAZAKI ,  Daisuke Sugiura ,  Takeo Maeda ,  Shiro Shibayama

IPC: C07K16/28 ,  A61K39/00 ,  A61P37/06

Abstract: The present application provides an immunosuppressive agent containing a substance that is selected from anti-CD80 antibodies and anti-PD-L1 antibodies and that promotes binding between PD-L1 and PD-1.