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公开(公告)号：US20240190975A1
公开(公告)日：2024-06-13
申请号：US18285304
申请日：2022-03-31
Applicant: Shionogi & Co., Ltd. , Osaka University
Inventor： Tetsuya Yoshida , Mai Yoshikawa , Miya Haruna , Morio Nagira , Koji Takahashi , Marina Hayashida , Hiroto Miwa , Yudai Sonoda , Naganari Ohkura , Shimon Sakaguchi , Hisashi Wada
IPC: C07K16/28 , A61K38/00 , A61K39/00 , C07K14/705 , C07K14/725
CPC classification number: C07K16/2866 , A61K39/4611 , A61K39/4612 , A61K39/4613 , A61K39/4631 , C07K14/70503 , C07K14/7051 , C07K14/70517 , C07K14/70521 , C07K14/70578 , A61K38/00 , A61K2239/13 , A61K2239/17 , A61K2239/21 , A61K2239/22 , C07K2317/24 , C07K2317/622 , C07K2319/02 , C07K2319/03
Abstract: The chimeric antigen receptor that recognizes CCR8 as an antigen of the present invention has cytotoxic activity against CCR8-expressing cells by being expressed in effector cells.
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公开(公告)号：US20200222463A1
公开(公告)日：2020-07-16
申请号：US16732764
申请日：2020-01-02
Applicant: Shionogi & Co., Ltd. , Osaka University
Inventor： Tetsuya Yoshida , Yujiro Kidani , Mitsunobu Matsumoto , Takayuki Kanazawa , Satomi Shinonome , Kanji Hojo , Naganari Ohkura , Shimon Sakaguchi , Atsushi Tanaka , Hisashi Wada , Atsunari Kawashima , Norio Nonomura
Abstract: The disclosure provides a pharmaceutical composition with a polypeptide that binds to a peptide produced by cDNA of GenBank ACC No. NM_005201.3 or NM_007720.2, and methods of use thereof.
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公开(公告)号：US11932696B2
公开(公告)日：2024-03-19
申请号：US17134775
申请日：2020-12-28
Applicant: Shionogi & Co., Ltd. , Osaka University
Inventor： Tetsuya Yoshida , Yujiro Kidani , Mitsunobu Matsumoto , Takayuki Kanazawa , Satomi Shinonome , Kanji Hojo , Naganari Ohkura , Shimon Sakaguchi , Atsushi Tanaka , Hisashi Wada , Atsunari Kawashima , Norio Nonomura
IPC: C07K16/28 , A61K9/00 , A61K35/17 , A61K39/00 , A61K47/60 , A61K47/64 , A61K47/68 , A61P35/00 , G01N33/50
CPC classification number: C07K16/2866 , A61K9/0019 , A61K35/17 , A61K47/60 , A61K47/6435 , A61K47/6883 , A61P35/00 , C07K16/2818 , C07K16/2827 , G01N33/5011 , A61K2039/505 , A61K2039/507 , A61K2039/572 , C07K2317/732 , C07K2317/76
Abstract: The present invention provides a pharmaceutical composition for cancer treatment comprising an antibody against CCR8.
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公开(公告)号：US20210115148A1
公开(公告)日：2021-04-22
申请号：US17134775
申请日：2020-12-28
Applicant: Shionogi & Co., Ltd. , Osaka University
Inventor： Tetsuya Yoshida , Yujiro Kidani , Mitsunobu Matsumoto , Takayuki Kanazawa , Satomi Shinonome , Kanji Hojo , Naganari Ohkura , Shimon Sakaguchi , Atsushi Tanaka , Hisashi Wada , Atsunari Kawashima , Norio Nonomura
Abstract: The present invention provides a pharmaceutical composition for cancer treatment comprising an antibody against CCR8.
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Patent Agency Ranking
公开(公告)号：US20210047421A1
公开(公告)日：2021-02-18
申请号：US17085040
申请日：2020-10-30
Applicant: Shionogi & Co., Ltd. , Osaka University
Inventor： Tetsuya Yoshida , Yujiro Kidani , Mitsunobu Matsumoto , Takayuki Kanazawa , Satomi Shinonome , Kanji Hojo , Naganari Ohkura , Shimon Sakaguchi , Atsushi Tanaka , Hisashi Wada , Atsunari Kawashima , Norio Nonomura
Abstract: The present invention provides a pharmaceutical composition for cancer treatment comprising an antibody against CCR8.
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公开(公告)号：US20200232973A1
公开(公告)日：2020-07-23
申请号：US16732850
申请日：2020-01-02
Applicant: Shionogi & Co., Ltd. , Osaka University
Inventor： Tetsuya Yoshida , Yujiro Kidani , Mitsunobu Matsumoto , Takayuki Kanazawa , Satomi Shinonome , Kanji Hojo , Naganari Ohkura , Shimon Sakaguchi , Atsushi Tanaka , Hisashi Wada , Atsunari Kawashima , Norio Nonomura
Abstract: The disclosure provides a method of measuring an efficacy of a drug composition for cancer and a method for treating a cancer by administering to a subject an effective amount of a pharmaceutical composition having a polypeptide that binds to a peptide produced by cDNA of GenBank ACC No. NM_005201.3 or NM_007720.2.
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公开(公告)号：US20220064312A1
公开(公告)日：2022-03-03
申请号：US17418417
申请日：2019-12-27
Applicant: Shionogi & Co., Ltd. , Osaka University
Inventor： Mai Yoshikawa , Tatsuya Takahashi , Junji Onoda , Sunao Imai , Etsuo Nakamura , Kentaro Furukawa , Tsuguo Miyauchi , Tetsuya Yoshida , Morio Nagira , Naganari Ohkura , Atsushi Tanaka , Shimon Sakaguchi , Hisashi Wada , Atsunari Kawashima
Abstract: Disclosed is a novel anti-CCR8 antibody. The antibody can be used for treating or preventing cancers or the like.
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公开(公告)号：US12259379B2
公开(公告)日：2025-03-25
申请号：US16626683
申请日：2018-06-29
Applicant: OSAKA UNIVERSITY
Inventor： Kota Iwahori , Hisashi Wada
IPC: G01N33/50 , A61K39/395 , C07K16/28 , C07K16/30 , G01N33/53 , G01N33/574 , G16B50/30 , G16H50/30 , A61K39/00
Abstract: An object of the present invention is to provide a companion diagnostic for predicting the effect of a tumor immunotherapy. The effect of a tumor immunotherapy is predicted by a method including step 1: contacting directly or indirectly peripheral blood mononuclear cells collected from a patient who is a target for treatment of a malignant tumor with tumor cells in vitro; step 2: determining whether the tumor cells that contacted with the peripheral blood mononuclear cells in step 1 are damaged; and step 3: determining that the tumor immunotherapy is effective against the malignant tumor in the patient when the tumor cells are determined to have been damaged in step 2.
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公开(公告)号：US10550191B2
公开(公告)日：2020-02-04
申请号：US16183216
申请日：2018-11-07
Applicant: SHIONOGI & CO., LTD. , OSAKA UNIVERSITY
Inventor： Tetsuya Yoshida , Yujiro Kidani , Mitsunobu Matsumoto , Takayuki Kanazawa , Satomi Shinonome , Kanji Hojo , Naganari Ohkura , Shimon Sakaguchi , Atsushi Tanaka , Hisashi Wada , Atsunari Kawashima , Norio Nonomura
Abstract: The present invention provides a pharmaceutical composition for cancer treatment comprising an antibody against CCR8.
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