公开(公告)号：US20250057928A1

公开(公告)日：2025-02-20

申请号：US18717944

申请日：2022-12-07

Applicant: OSAKA UNIVERSITY ,  FunPep Co., Ltd.

Inventor： Hironori NAKAGAMI ,  Hiroki HAYASHI ,  Ryuichi MORISHITA ,  Makoto SAKAGUCHI ,  Sotaro KAWABATA

IPC: A61K39/00 ,  A61K47/62

Abstract: The present invention provides a vaccine composition containing a complex of a T cell receptor antigen peptide and a B cell receptor antigen peptide and capable of inducing the production of an antibody against IL-23, wherein the B cell receptor antigen peptide is represented by the following formula (I): X1-X2-X3-X4-X5-X6-X7-X8   (I) wherein X1 is S, A, G, T, K, or R, X2 is P, A, G, S, T, K, or R, X3 is S, A, G, T, K, or R, X4 is Q, A, G, T, or N, X5 is P, A, G, S, T, Q, or N, X6 is W, A, Y, or E, X7 is Q, A, G, T, or N, and X8 is R, A, G, or K.