公开(公告)号：US10441613B2

公开(公告)日：2019-10-15

申请号：US15754687

申请日：2016-08-23

Applicant: OSAKA UNIVERSITY ,  GenomIdea Inc.

Inventor： Yasufumi Kaneda ,  Toshihiro Nakajima

IPC: A61K39/00 ,  A61K48/00 ,  C12Q1/68 ,  A61K38/00 ,  A61K35/76 ,  A61K38/19 ,  A61K45/00 ,  A61K31/7088 ,  A61K31/713 ,  A61K31/739 ,  A61P35/00 ,  C12N7/00

Abstract: The present invention provides, as a new anti-cancer agent obtained by combining HVJ-E and a molecule synergistically acting therewith, an anti-cancer agent containing the following (1) and (2): (1) HVJ-E (hemagglutinating virus of Japan envelope), (2) CXCL2, a nucleic acid comprising a base sequence encoding CXCL2 or a CXCL2 expression inducing agent.

公开(公告)号：US11166995B2

公开(公告)日：2021-11-09

申请号：US16346576

申请日：2017-11-01

Applicant: OSAKA UNIVERSITY ,  GENOMIDEA INC.

Inventor： Yasufumi Kaneda ,  Kazuma Sakura ,  Tomoyuki Nishikawa ,  Masanori Fukushima ,  Toshihiro Nakajima

IPC: A61K35/76 ,  A61P35/00 ,  C12N7/00 ,  A61K39/395 ,  A61K31/7105 ,  A61K45/00 ,  A61P43/00 ,  A61K31/711 ,  A61P35/02 ,  A61P37/04

Abstract: The present invention provides an anticancer agent containing the following (1) and (2):
(1) HVJ-E (hemagglutinating virus of Japan envelope),
(2) an inhibitor of an immune checkpoint protein.