公开(公告)号：US20190156479A1

公开(公告)日：2019-05-23

申请号：US16092036

申请日：2017-04-20

申请人： OSLO UNIVERSITETSSYKEHUS HF ,  AKERSHUS UNIVERSITETSSYKEHUS HF

发明人： Kjell-Inge GJESDAL ,  Endre GRØVIK ,  Kathrine Røe REDALEN ,  Tryggve Holck STORÅS

IPC分类号： G06T7/00 ,  A61B5/055 ,  A61B5/00

摘要： Dynamic contrast enhanced MRI data and dynamic susceptibility contrast MRI data for a volume of the patient's body including a tumor are used in order to identify the risk of lymph node metastasis. A volume of interest enclosing the tumor is identified and the MRI data for the volume of interest is processed in order to identify one or more parameters relating to the transverse relaxation rate and/or to dynamic changes in the transverse relaxation rate. A comparison is made to previously obtained similar parameters for other patients having similar tumors that are either known to exhibit lymph node metastasis or are known not to exhibit lymph node metastasis in order to determine if the MRI data indicates that the patient has a tumor at greater risk of exhibiting lymph node metastasis or a tumor with a lesser risk of exhibiting lymph node metastasis.

公开(公告)号：US20230203592A1

公开(公告)日：2023-06-29

申请号：US17923331

申请日：2021-05-05

申请人： Akershus Universitetssykehus HF

发明人： Anne Hansen REE ,  Anna Paula BOUSQUET ,  Tonje BJØRNETRØ ,  Sebastian MELTZER ,  Kathrine Røe REDALEN

IPC分类号： C12Q1/6886

CPC分类号： C12Q1/6886 ,  C12Q2600/156 ,  C12Q1/6844

摘要： The present invention relates to compositions and methods for characterizing cancer. In particular, the present invention relates to compositions and methods for identifying bowel cancers at increased risk of metastasis.