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公开(公告)号：US10941169B2
公开(公告)日：2021-03-09
申请号：US16878109
申请日：2020-05-19
发明人： Hiroaki Yuasa , Hiroki Okazaki
IPC分类号： C07F9/6571 , A61P19/00 , A61P29/00 , A61P35/00 , C07F9/6574 , A61K31/665
摘要： An object of the present invention is to provide crystal of a cyclic phosphonic acid sodium salt (2ccPA) with high purity and excellent storage stability and a method for producing the crystal. The present invention provides a crystal of a cyclic phosphonic acid sodium salt (2ccPA) represented by formula (1):
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公开(公告)号：US10774100B2
公开(公告)日：2020-09-15
申请号：US16460332
申请日：2019-07-02
发明人： Hiroaki Yuasa , Hiroki Okazaki
IPC分类号： C07F9/6571 , A61P19/00 , A61P29/00 , A61P35/00 , C07F9/6574 , A61K31/665
摘要： An object t of the present invention is to proroaide crystal of a cyclic phosphonic acid sodium salt (2ccPA) with high purity and excellent storage stability and a method for producing the crystal. The present invention provides a crystal of a cyclic phosphonic acid sodium salt (2ccPA) represented by formula (1):
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公开(公告)号：US10385081B2
公开(公告)日：2019-08-20
申请号：US15872321
申请日：2018-01-16
发明人： Hiroaki Yuasa , Hiroki Okazaki
IPC分类号： C07F9/6571 , C07F9/6574 , A61P19/00 , A61P29/00 , A61P35/00 , A61K31/665
摘要： An object of the present invention is to provide a crystal of a cyclic phosphonic acid sodium salt (2ccPA) with high purity and excellent storage stability and a method for producing the crystal. The present invention provides a crystal of a cyclic phosphonic acid sodium salt (2ccPA) represented by formula (1):
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公开(公告)号：US09908909B2
公开(公告)日：2018-03-06
申请号：US15501525
申请日：2015-08-12
发明人： Hiroaki Yuasa , Hiroki Okazaki
IPC分类号： C07F9/6571
CPC分类号： C07F9/657163 , A61K31/665 , A61P19/00 , A61P29/00 , A61P35/00 , C07B2200/13 , C07F9/657181 , C07F9/65742
摘要： An object of the present invention is to provide a crystal of a cyclic phosphonic acid sodium salt (2ccPA) with high purity and excellent storage stability and a method for producing the crystal. The present invention provides a crystal of a cyclic phosphonic acid sodium salt (2ccPA) represented by formula (1):
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公开(公告)号：US11958876B2
公开(公告)日：2024-04-16
申请号：US17787522
申请日：2020-12-23
发明人： Shin Yoneyama , Hiroki Okazaki
IPC分类号： C07F9/6574
CPC分类号： C07F9/65742
摘要： Provided is a degradation inhibitor that delays the progress of the degradation reaction of 2ccPA and has an excellent stabilization effect by using a carbacyclic phosphatidic acid compound represented by formula (1):
wherein R1 represents hydrogen, alkali metal, alkyl, arylalkyl, or aryl; bonds indicated by solid and dotted lines represent single or double bonds; wavy lines represent single bonds; and when the single bond is adjacent to a double bond, the steric configuration is E-configuration, Z-configuration, or any mixture thereof.-
公开(公告)号：US11168101B2
公开(公告)日：2021-11-09
申请号：US16877915
申请日：2020-05-19
发明人： Hiroaki Yuasa , Hiroki Okazaki
IPC分类号： C07F9/6571 , A61P19/00 , A61P29/00 , C07F9/6574 , A61P35/00 , A61K31/665
摘要： An object t of the present invention is to provide crystal of a cyclic phosphonic acid sodium salt (2ccPA) with high purity and excellent storage stability and a method for producing the crystal. The present invention provides a crystal of a cyclic phosphonic acid sodium salt (2ccPA) represented by formula (1):
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公开(公告)号：US20180208614A1
公开(公告)日：2018-07-26
申请号：US15872321
申请日：2018-01-16
发明人： Hiroaki Yuasa , Hiroki Okazaki
IPC分类号： C07F9/6571
CPC分类号： C07F9/657163 , A61K31/665 , A61P19/00 , A61P29/00 , A61P35/00 , C07B2200/13 , C07F9/657181 , C07F9/65742
摘要： An object of the present invention is to provide a crystal of a cyclic phosphonic acid sodium salt (2ccPA) with high purity and excellent storage stability and a method for producing the crystal. The present invention provides a crystal of a cyclic phosphonic acid sodium salt (2ccPA) represented by formula (1):
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