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公开(公告)号:US10221450B2
公开(公告)日:2019-03-05
申请号:US14773164
申请日:2014-01-22
发明人: Andrew John Heron , David Antoni Alves , James Anthony Clarke , Marion Louise Crawford , Daniel Ryan Garalde , Graham Hall , Daniel John Turner , James White
IPC分类号: C12Q1/68 , C12Q1/6869 , C12Q1/6827 , C12N9/14 , C12N13/00
摘要: The invention relates to new methods of moving helicases past spacers on polynucleotides and controlling the loading of helicases on polynucleotides. The invention also relates to new methods of characterizing target polynucleotides using helicases.
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公开(公告)号:US20170067101A1
公开(公告)日:2017-03-09
申请号:US15120186
申请日:2015-02-19
IPC分类号: C12Q1/68
摘要: The invention relates to an improved method for characterising a template polynucleotide. The method involves using a polymerase to prepare a modified polynucleotide which makes it easier to characterise than the template polynucleotide.
摘要翻译: 本发明涉及用于表征模板多核苷酸的改进方法。 该方法涉及使用聚合酶来制备修饰的多核苷酸,使其比模板多核苷酸更易于表征。
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