公开(公告)号：US08519101B2

公开(公告)日：2013-08-27

申请号：US13764124

申请日：2013-02-11

Applicant: Okamoto Corporation

Inventor： Tianfu Zhao ,  Masao Nakagaki

IPC: A61K38/39 ,  C12P21/02 ,  C12N15/12 ,  C12N15/85 ,  C12N15/89

CPC classification number: C07K14/43518 ,  A01K67/0333 ,  A01K67/0339 ,  A01K2217/052 ,  A01K2227/706 ,  A01K2267/01 ,  A01K2267/02 ,  C12N15/8509

Abstract: Disclosed are a protein encoded by any one of nucleic acids (i) to (iv): (i) a nucleic acid having a base sequence of SEQ ID NO: 1; (ii) a nucleic acid encoding a protein having an amino acid sequence of SEQ ID NO: 2; (iii) a nucleic acid encoding a dragline protein and having a sequence identity of 90% or more with the nucleic acid (i); (iv) a nucleic acid which encodes a dragline protein and hybridizes with a complementary chain of the nucleic acid (i) under stringent conditions, and a silk thread containing the protein.

Abstract translation: 公开了由核酸（i）至（iv）中的任一种编码的蛋白质：（i）具有SEQ ID NO：1的碱基序列的核酸; （ii）编码具有SEQ ID NO：2的氨基酸序列的蛋白质的核酸; （iii）编码牵引蛋白并与核酸（i）具有90％或更高的序列同一性的核酸; （iv）编码牵引蛋白并在严格条件下与核酸（i）的互补链杂交的核酸和含有蛋白质的丝线。