摘要:
A novel use for the class of biologically active bis-heterocyclic, e.g., bis-indole alkaloid compounds, which have been named topsentins, nortopsentins, hamacanthins, or dragmacidins, pharmaceutical compositions containing them, methods of producing the compounds, and methods of using the compounds are disclosed. Specifically, the novel utility pertains to the anti-inflammatory properties exhibited by the bis-indole compounds and their analogs.
摘要:
A novel use for the class of biologically active bis-heterocyclic, e.g., bis-indole alkaloid compounds, which have been named topsentins, nortopsentins, hamacanthins, or dragmacidins, pharmaceutical compositions containing them, methods of producing the compounds, and methods of using the compounds are disclosed. Specifically, the novel utility pertains to the anti-inflammatory properties exhibited by the bis-indole compounds and their analogs.
摘要:
A novel use for the class of biologically active bis-indole alkaloid compounds, which have been named topsentins, nortopsentins, or dragmacidins, pharmaceutical compositions containing them, methods of producing the compounds, and methods of using the compounds are disclosed. Specifically, the novel utility pertains to the anti-inflammatory properties exhibited by the bis-indole compounds and their analogs.
摘要:
Method and system for creating and distributing professional quality electronic postcards are provided. An accessible library of numerous photographs/videos taken by professionals is maintained, for example, on a app or website. Access to the app or website can be accomplished using any suitable input device, for example smart phones, tablets, laptops, computers etc. Following a series of simple steps, users select from an assortment of images, videos, photos, messages, etc., to create an electronic postcard. Users have their own pages on the app or website, where sent and received electronic postcards are stored. A simple method for creating albums from the user's electronic postcards is also provided.
摘要:
Compounds according to Formula (I): wherein R1, R2, R3, and R4 are as defined in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
摘要:
Compounds of formula (I), wherein D, Ar1, E and Ar2 are as defined in the specification, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, especially in the treatment or prophylaxis of psychotic and intellectual impairment disorders.
摘要:
According to some embodiments, systems and apparatus for enhanced mobile computing platforms are provided. For example, an apparatus or system may comprise a universal computational package, comprising a processor, a memory coupled to the processor, a plurality of instructions stored in the memory directed to at least one specific use of the universal computational package, and a plurality of interface controllers coupled to the processor, wherein each of the plurality of interface controllers is operable to cause the processor to execute the plurality of stored instructions in accordance with the presence of a use-specific user interface cover associated with the at least one specific use of the universal computational package.
摘要:
Apparatus and method for playing an anagram-type game in a game show or computer game format. One or more anagrams, each comprised of scrambled letters, are displayed on a gameboard. At least one object of the game is to guess the unscrambled solution to each anagram. When correctly guessed, the letters are moved from their scrambled configuration to their unscrambled configuration. An ultimate solution to the puzzle is preferrably revealed by some of the letters of the collective unscrambled anagrams which are moved into a predetermined alignment. Several means are included for making it easier to view, study and follow the progress of the game such as moving each letter along a path, leaving outlines of the letters in their initial positions, and indicating which anagram is to be guessed by a player.
摘要:
This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent. The exemplary compounds have the following formula: wherein X is selected from the group consisting of substituted phenyl, substituted or unsubstituted heteroaryl and unsubstituted cycloalkyl; R3a is selected from the group consisting of H, unsubstituted C1 or C2 or C3 or C4 or C5 or C6 alkyl and unsubstituted C3 or C4 or C5 or C6 cycloalkyl; R3b is selected from the group consisting of H, unsubstituted C1 or C2 or C3 or C4 or C5 or C6 alkyl and unsubstituted C3 or C4 or C5 or C6 cycloalkyl; with the proviso that R3a and R3b, along with the atom to which they are attached, are optionally joined to form a 3 or 4 or 5 or 6 membered ring, with the proviso that R3a and R3b cannot both be H, or a salt thereof.
摘要:
The present invention relates to novel molecular probes having the formula (I) (I) useful for the characterization, detection, localization and isolation of the γ-secretase enzyme.