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公开(公告)号:US09623070B2
公开(公告)日:2017-04-18
申请号:US15234195
申请日:2016-08-11
申请人: Oncolmmune, Inc.
发明人: Yang Liu , Yin Wang , Yan Liu , Sami N. Malek , Pan Zheng
CPC分类号: A61K38/07 , A61K31/00 , A61K31/395 , A61K31/4355 , A61K31/498 , A61K31/565 , A61K38/08 , A61K45/06 , A61K2300/00
摘要: The present invention relates to treating a hematologic cancer using a Hypoxia-Inducible Factor (HIF inhibitor). The invention also relates to inducing acute myeloid leukemia remission using the HIF inhibitor. The invention further relates to inhibiting a maintenance or survival function of a cancer stem cell (CSC) using the HIF inhibitor.