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公开(公告)号:US09133150B2
公开(公告)日:2015-09-15
申请号:US13951720
申请日:2013-07-26
申请人: Orbital ATK, Inc.
发明人: Mark D. Bednarski , Susan Knox , Louis F. Cannizzo , Kirstin F. Warner , Robert B. Wardle , Stephen P. Velarde , Shoucheng Ning
IPC分类号: C07D307/02 , C07D305/00 , C07D407/00 , C07D493/00 , A01N43/02 , A61K31/335 , C07D303/22 , A61K31/21 , A61K31/336 , A61K31/38 , A61K31/395 , A61K45/06
CPC分类号: C07D303/22 , A61K31/21 , A61K31/336 , A61K31/38 , A61K31/395 , A61K45/06
摘要: The present invention provides O-nitro compounds, pharmaceutical compositions of O-nitro compounds and methods of using O-nitro compounds and/or pharmaceutical compositions thereof to treat or prevent diseases or disorders characterized by abnormal cell proliferation, such as cancer, inflammation, cardiovascular disease and autoimmune disease.
摘要翻译: 本发明提供O-硝基化合物,O-硝基化合物的药物组合物和使用O-硝基化合物和/或其药物组合物的方法来治疗或预防以异常细胞增殖为特征的疾病或病症,例如癌症,炎症,心血管 疾病和自身免疫性疾病。