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1.发明申请公开(公告)号：US20220009944A1
公开(公告)日：2022-01-13
申请号：US17470608
申请日：2021-09-09
发明人： Christopher M. Beaudry , Xuan Ju
IPC分类号： C07D498/06 , C07D491/153
摘要： Disclosed herein are embodiments of a compound having a Formula I or a salt, solvate, N-oxide, prodrug, diastereomer or enantiomer thereof. Also disclosed are derivative compounds made from the compound of Formula I. Certain derivative compounds have a Formula V-2, or a salt, solvate, N-oxide, prodrug, diastereomer or enantiomer thereof. Also disclosed are method for making and using the disclosed compounds. Certain disclosed embodiments are useful for treating and/or preventing certain diseases and/or disorders, including proliferation diseases, such as leukemia.
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2.发明授权公开(公告)号：US11708377B2
公开(公告)日：2023-07-25
申请号：US17470608
申请日：2021-09-09
发明人： Christopher M. Beaudry , Xuan Ju
IPC分类号： C07D498/06 , C07D491/153
CPC分类号： C07D498/06 , C07D491/153
摘要： Disclosed herein are embodiments of a compound having a Formula I
or a salt, solvate, N-oxide, prodrug, diastereomer or enantiomer thereof. Also disclosed are derivative compounds made from the compound of Formula I. Certain derivative compounds have a Formula V-2, or a salt, solvate, N-oxide, prodrug, diastereomer or enantiomer thereof.
Also disclosed are method for making and using the disclosed compounds. Certain disclosed embodiments are useful for treating and/or preventing certain diseases and/or disorders, including proliferation diseases, such as leukemia.-
公开(公告)号：US20230117370A1
公开(公告)日：2023-04-20
申请号：US18046583
申请日：2022-10-14
IPC分类号： C07C37/07 , C07D307/83
摘要： Disclosed herein are embodiments of a method for making substituted compounds with specific and selectable regiochemistry. Also disclosed are compounds made by the method. The method may comprise contacting a compound having a formula I with a compound according to formula II in the presence of a Lewis acid to form a phenol compound according to formula III and/or a benzofuranone compound according to formula IV
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