公开(公告)号：US20110301704A1

公开(公告)日：2011-12-08

申请号：US13094145

申请日：2011-04-26

申请人： Ottavio Alfieri ,  Alain F. Carpentier ,  Francesco Maisano ,  Patrick McCarthy ,  Alberto Redaelli

发明人： Ottavio Alfieri ,  Alain F. Carpentier ,  Francesco Maisano ,  Patrick McCarthy ,  Alberto Redaelli

IPC分类号： A61F2/24

CPC分类号： A61F2/2448 ,  A61F2/2409 ,  A61F2/246

摘要： A remodeling mitral annuloplasty ring with a reduced anterior-to-posterior dimension to restore coaptation between the mitral leaflets in mitral valve insufficiency (IMVI). The ring has a generally oval shaped body with a major axis perpendicular to a minor axis, both perpendicular to a blood flow axis. An anterior section lies between anteriolateral and posteriomedial trigones, while a posterior section defines the remaining ring body and is divided into P1, P2, and P3 segments corresponding to the three scallops of the same nomenclature in the posterior leaflet of the mitral valve. The anterior-to-posterior dimension of the ring body is reduced from conventional rings; such as by providing, in atrial plan view, a pulled-in P3 segment. Viewed another way, the convexity of the P3 segment is less pronounced than the convexity of the P1 segment. In addition, the ring body may have a downwardly deflected portion in the posterior section, preferably within the P2 and P3 segments. The downwardly deflected portion may have an apex which is the lowest elevation of the ring body and may be offset with respect to the center of the downwardly deflected portion toward the P1 segment. A sewing cuff may have an enlarged radial dimension of between 5-10 cm, or only a portion of the sewing cuff may be enlarged.

摘要翻译： 重建二尖瓣瓣环成形术环，具有减小的前后尺寸，以恢复二尖瓣关闭不全（IMVI）中的二尖瓣小叶之间的接合。 环具有大致椭圆形的主体，其长轴垂直于短轴，两者垂直于血流轴线。 前部位于前外侧和后内侧三角形之间，而后段限定剩余的环体，并分为对应于二尖瓣后叶中相同命名的三扇贝的P1，P2和P3段。 环体的前后尺寸从常规环减少; 例如通过在心房平面图中提供一个拉入的P3段。 换句话说，P3段的凸度比P1段的凸度更不明显。 此外，环体可以在后部中具有向下偏转的部分，优选地在P2和P3段内。 向下偏转的部分可以具有作为环主体的最低高度的顶点，并且可以相对于朝向P1段的向下偏转部分的中心偏移。 缝制袖口可以具有在5-10cm之间的放大的径向尺寸，或者仅可以扩大一部分缝合袖口。

公开(公告)号：US07935145B2

公开(公告)日：2011-05-03

申请号：US10882031

申请日：2004-06-30

申请人： Ottavio Alfieri ,  Alain F. Carpentier ,  Francesco Maisano ,  Patrick McCarthy ,  Alberto Redaelli

发明人： Ottavio Alfieri ,  Alain F. Carpentier ,  Francesco Maisano ,  Patrick McCarthy ,  Alberto Redaelli

IPC分类号： A61F2/24

CPC分类号： A61F2/2448 ,  A61F2/2409

摘要： A remodeling mitral annuloplasty ring with a reduced anterior-to-posterior dimension to restore coaptation between the mitral leaflets in mitral valve insufficiency (IMVI). The ring has a generally oval shaped body with a major axis perpendicular to a minor axis, both perpendicular to a blood flow axis. An anterior section lies between anteriolateral and posteriomedial trigones, while a posterior section defines the remaining ring body and is divided into P1, P2, and P3 segments corresponding to the three scallops of the same nomenclature in the posterior leaflet of the mitral valve. The anterior-to-posterior dimension of the ring body is reduced from conventional rings; such as by providing, in atrial plan view, a pulled-in P3 segment. Viewed another way, the convexity of the P3 segment is less pronounced than the convexity of the P1 segment. In addition, the ring body may have a downwardly deflected portion in the posterior section, preferably within the P2 and P3 segments. The downwardly deflected portion may have an apex which is the lowest elevation of the ring body and may be offset with respect to the center of the downwardly deflected portion toward the P1 segment. A sewing cuff may have an enlarged radial dimension of between 5-10 cm, or only a portion of the sewing cuff may be enlarged.

摘要翻译： 重建二尖瓣瓣环成形术环，具有减小的前后尺寸，以恢复二尖瓣关闭不全（IMVI）中的二尖瓣小叶之间的接合。 环具有大致椭圆形的主体，其长轴垂直于短轴，两者垂直于血流轴线。 前部位于前外侧和后内侧三角形之间，而后段限定剩余的环体，并分为对应于二尖瓣后叶中相同命名的三扇贝的P1，P2和P3段。 环体的前后尺寸从常规环减少; 例如通过在心房平面图中提供一个拉入的P3段。 换句话说，P3段的凸度比P1段的凸度更不明显。 此外，环体可以在后部中具有向下偏转的部分，优选地在P2和P3段内。 向下偏转的部分可以具有作为环主体的最低高度的顶点，并且可以相对于朝向P1段的向下偏转部分的中心偏移。 缝制袖口可以具有在5-10cm之间的放大的径向尺寸，或者仅可以扩大一部分缝合袖口。

公开(公告)号：US20050131533A1

公开(公告)日：2005-06-16

申请号：US10882031

申请日：2004-06-30

申请人： Ottavio Alfieri ,  Alain Carpentier ,  Francesco Maisano ,  Patrick McCarthy ,  Alberto Redaelli

发明人： Ottavio Alfieri ,  Alain Carpentier ,  Francesco Maisano ,  Patrick McCarthy ,  Alberto Redaelli

IPC分类号： A61F2/24

CPC分类号： A61F2/2448 ,  A61F2/2409

摘要： A remodeling mitral annuloplasty ring with a reduced anterior-to-posterior dimension to restore coaptation between the mitral leaflets in mitral valve insufficiency (IMVI). The ring has a generally oval shaped body with a major axis perpendicular to a minor axis, both perpendicular to a blood flow axis. An anterior section lies between anteriolateral and posteriomedial trigones, while a posterior section defines the remaining ring body and is divided into P1, P2, and P3 segments corresponding to the three scallops of the same nomenclature in the posterior leaflet of the mitral valve. The anterior-to-posterior dimension of the ring body is reduced from conventional rings; such as by providing, in atrial plan view, a pulled-in P3 segment. Viewed another way, the convexity of the P3 segment is less pronounced than the convexity of the P1 segment. In addition, the ring body may have a downwardly deflected portion in the posterior section, preferably within the P2 and P3 segments. The downwardly deflected portion may have an apex which is the lowest elevation of the ring body and may be offset with respect to the center of the downwardly deflected portion toward the P1 segment. A sewing cuff may have an enlarged radial dimension of between 5-10 cm, or only a portion of the sewing cuff may be enlarged.

摘要翻译： 重建二尖瓣瓣环成形术环，具有减小的前后尺寸，以恢复二尖瓣关闭不全（IMVI）中的二尖瓣小叶之间的接合。 环具有大致椭圆形的主体，其长轴垂直于短轴，两者垂直于血流轴线。 前段位于前外侧和后内侧三角形之间，而后段限定剩余的环体，并分为对应于二尖瓣后叶中相同命名的三扇贝的P 1，P 2和P 3段 。 环体的前后尺寸从常规环减少; 例如通过在心房平面图中提供一个拉入的P 3区段。 换句话说，P 3段的凸度比P 1段的凸度更不明显。 此外，环体可以在后部中具有向下偏转的部分，优选地在P 2和P 3段内。 向下偏转的部分可以具有顶点，其是环体的最低高度，并且可以相对于朝向P 1段的向下偏转部分的中心偏移。 缝制袖口可以具有在5-10cm之间的放大的径向尺寸，或者仅可以扩大一部分缝合袖口。

公开(公告)号：US06726717B2

公开(公告)日：2004-04-27

申请号：US10144932

申请日：2002-05-15

申请人： Ottavio Alfieri ,  Francesco Maisano ,  Alberto Redaelli

发明人： Ottavio Alfieri ,  Francesco Maisano ,  Alberto Redaelli

IPC分类号： A61F224

CPC分类号： A61F2/2448

摘要： The present invention refers to an annular prosthesis for mitral valve. In one of its embodiments the annular prosthesis for mitral valve is made up of a posterior half-ring and an anterior half-ring coupled to each other on a first transverse plane which defines a maximum width section of the prosthesis, characterised in that the ratio between the distance between said anterior half-ring and said posterior half-ring, as measured along a second plane, perpendicular to said first plane and equidistant to said couplings, and said maximum width of the prosthesis is lower than 3/4.

摘要翻译： 本发明涉及一种二尖瓣环形假体。 在其一个实施例中，二尖瓣的环形假体由在限定假体的最大宽度部分的第一横向平面上彼此联接的后半环和前半环组成，其特征在于， 在所述前半环和所述后半环之间的距离，沿着垂直于所述第一平面并等距于所述联接件的第二平面测量，并且所述假体的所述最大宽度低于3/4。

公开(公告)号：US20100137980A1

公开(公告)日：2010-06-03

申请号：US12697936

申请日：2010-02-01

申请人： Ottavio Alfieri ,  Francesco Maisano ,  Alberto Redaelli

发明人： Ottavio Alfieri ,  Francesco Maisano ,  Alberto Redaelli

IPC分类号： A61F2/24

CPC分类号： A61F2/2448

摘要： An annular prosthesis for a mitral valve that may include a posterior half-ring and an anterior half-ring coupled to each other on a first transverse plane which defines a maximum width section of the prosthesis. The ratio between the distance between the anterior half-ring and the posterior half-ring, as measured along a second plane, perpendicular to the first plane and equidistant to the couplings, and the maximum width of the prosthesis is lower than ¾.

摘要翻译： 用于二尖瓣的环形假体，其可以包括在限定假体的最大宽度部分的第一横向平面上彼此耦合的后半环和前半环。 沿着第二平面测量的前半环和后半环之间的距离与第一平面垂直并且等距于联轴器的距离以及假体的最大宽度之间的比值小于3。

公开(公告)号：US08529621B2

公开(公告)日：2013-09-10

申请号：US13416929

申请日：2012-03-09

申请人： Ottavio Alfieri ,  Francesco Maisano ,  Alberto Redaelli

发明人： Ottavio Alfieri ,  Francesco Maisano ,  Alberto Redaelli

IPC分类号： A61F2/24

CPC分类号： A61F2/2448

摘要： The present invention refers to an annular prosthesis for mitral valve. In one of its embodiments the annular prosthesis for mitral valve is made up of a posterior half-ring and an anterior half-ring coupled to each other on a first transverse plane which defines a maximum width section of the prosthesis, characterized in that the ratio between the distance between said anterior half-ring and said posterior half-ring, as measured along a second plane, perpendicular to said first plane and equidistant to said couplings, and said maximum width of the prosthesis is lower than ¾.

摘要翻译： 本发明涉及一种二尖瓣环形假体。 在其一个实施例中，二尖瓣的环形假体由在限定假体的最大宽度部分的第一横向平面上彼此联接的后半环和前半环组成，其特征在于， 在所述前半环和所述后半环之间的距离，沿着垂直于所述第一平面并等距于所述联接件的第二平面测量，并且所述假体的所述最大宽度低于¾。

公开(公告)号：US20120172983A1

公开(公告)日：2012-07-05

申请号：US13416929

申请日：2012-03-09

申请人： Ottavio Alfieri ,  Francesco Maisano ,  Alberto Redaelli

发明人： Ottavio Alfieri ,  Francesco Maisano ,  Alberto Redaelli

IPC分类号： A61F2/24

CPC分类号： A61F2/2448

摘要： The present invention refers to an annular prosthesis for mitral valve. In one of its embodiments the annular prosthesis for mitral valve is made up of a posterior half-ring and an anterior half-ring coupled to each other on a first transverse plane which defines a maximum width section of the prosthesis, characterised in that the ratio between the distance between said anterior half-ring and said posterior half-ring, as measured along a second plane, perpendicular to said first plane and equidistant to said couplings, and said maximum width of the prosthesis is lower than 3/4.

摘要翻译： 本发明涉及一种二尖瓣环形假体。 在其一个实施例中，二尖瓣的环形假体由在限定假体的最大宽度部分的第一横向平面上彼此联接的后半环和前半环组成，其特征在于， 在所述前半环和所述后半环之间的距离，沿着垂直于所述第一平面并等距于所述联接件的第二平面测量，并且所述假体的所述最大宽度低于3/4。

公开(公告)号：US07674286B2

公开(公告)日：2010-03-09

申请号：US10742454

申请日：2003-12-18

申请人： Ottavio Alfieri ,  Francesco Maisano ,  Alberto Redaelli

发明人： Ottavio Alfieri ,  Francesco Maisano ,  Alberto Redaelli

IPC分类号： A61F2/24

CPC分类号： A61F2/2448

摘要： An annular prosthesis for a mitral valve that may include a posterior half-ring and an anterior half-ring coupled to each other on a first transverse plane which defines a maximum width section of the prosthesis. The ratio between the distance between the anterior half-ring and the posterior half-ring, as measured along a second plane, perpendicular to the first plane and equidistant to the couplings, and the maximum width of the prosthesis is lower than 3/4.

摘要翻译： 用于二尖瓣的环形假体，其可以包括在限定假体的最大宽度部分的第一横向平面上彼此耦合的后半环和前半环。 前半环和后半环之间的距离，沿垂直于第一平面并等距于联轴器的第二平面和假体的最大宽度测量的距离小于3/4。

公开(公告)号：US20050004666A1

公开(公告)日：2005-01-06

申请号：US10742454

申请日：2003-12-18

申请人： Ottavio Alfieri ,  Francesco Maisano ,  Alberto Redaelli

发明人： Ottavio Alfieri ,  Francesco Maisano ,  Alberto Redaelli

IPC分类号： A61F2/24

CPC分类号： A61F2/2448

摘要： An annular prosthesis for a mitral valve that may include a posterior half-ring and an anterior half-ring coupled to each other on a first transverse plane which defines a maximum width section of the prosthesis. The ratio between the distance between the anterior half-ring and the posterior half-ring, as measured along a second plane, perpendicular to the first plane and equidistant to the couplings, and the maximum width of the prosthesis is lower than 3/4.

摘要翻译： 用于二尖瓣的环形假体，其可以包括在限定假体的最大宽度部分的第一横向平面上彼此耦合的后半环和前半环。 前半环和后半环之间的距离，沿垂直于第一平面并等距于联轴器的第二平面和假体的最大宽度测量的距离小于3/4。

公开(公告)号：US08388566B2

公开(公告)日：2013-03-05

申请号：US12899283

申请日：2010-10-06

申请人： Stefano Reggiani ,  Claudio Silvestri ,  Alberto Giri ,  Alberto Redaelli ,  Gianfranco Beniamino Fiore

发明人： Stefano Reggiani ,  Claudio Silvestri ,  Alberto Giri ,  Alberto Redaelli ,  Gianfranco Beniamino Fiore

IPC分类号： A61M37/00

CPC分类号： A61M1/1698 ,  A61M1/322 ,  A61M1/3627

摘要： An oxygenator combines, in a single structure, a heat exchanger, a gas exchanger, an arterial filter, and a filter frame. Such an oxygenator permits fewer fluid connections and thus may simplify an extracorporeal blood circuit, including a heart-lung machine and a blood reservoir, in which it is used. In some embodiments, the oxygenator may be configured to include multiple purge ports for purging bubbles both before and after filtering the blood.