公开(公告)号：US20230398162A1

公开(公告)日：2023-12-14

申请号：US18034746

申请日：2021-10-19

Applicant: Oxana Karpf

Inventor： Oxana Karpf

IPC: A61K35/76 ,  C12N7/00

CPC classification number: A61K35/76 ,  C12N7/00 ,  C12N2795/00032

Abstract: The invention relates to a method for reducing the population of at least one intestinal and/or gastrointestinal species of bacteria, the method comprising the following steps:



a) providing a biological sample containing bacteria of at least one intestinal and/or gastrointestinal species of bacteria, the intestinal and/or gastrointestinal species of bacteria directly or indirectly influencing a psychological, neurodegenerative and/or neurological illness and/or disorder of a host organism; and
b) providing bacteriophages of at least one species of bacteriophages that are specific to the intestinal and/or gastrointestinal species of bacteria and that comprise at least one nucleic acid functionally associated with a promotor and/or a regulatory element; and
c) contacting and incubating the biological sample with the bacteriophages, the incubation continuing until the population of the intestinal and/or gastrointestinal species of bacteria has been reduced by at least 70%.