公开(公告)号：US11413272B2

公开(公告)日：2022-08-16

申请号：US16616515

申请日：2018-05-25

申请人： Oxford University Innovation Limited

发明人： Tharindi Panduwawala ,  Peter Brandt ,  David Wang ,  Mounir Andaloussi ,  Jürgen Brem ,  Christopher J. Schofield

IPC分类号： C07D207/34 ,  A61K31/403 ,  A61P31/04 ,  A61K31/401 ,  A61K31/4025 ,  A61K31/407 ,  A61K31/4164 ,  C07D209/42 ,  C07D209/70 ,  C07D233/90 ,  C07D405/04

摘要： The present invention relates to compounds of Formula (I) that function as inhibitors of bacterial metallo-beta-lactamases. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of a bacterial infection. (Formula (I))