公开(公告)号：US20170260187A1

公开(公告)日：2017-09-14

申请号：US15511697

申请日：2014-10-28

申请人： PÉCSI TUDOMÁNYEGYETEM ,  VICHEM CHEMIE KUTATÓ KFT.

发明人： János SZOLCSÁNYI ,  Erika PINTÉR ,  Zsuzsanna HELYES ,  Éva SZÖKE ,  Frigyes WÁCZEK ,  László ÖRFI ,  György KÉRI ,  Tamás SZÜTS

IPC分类号： C07D487/00

CPC分类号： C07D487/00

摘要： The present invention relates to 4-phenetylamino-7H-pyrrolo[2,3-d]pyrimidine derivatives of the and solvates, hydrates and pharmaceutically acceptable salts thereof, processes for manufacturing of them, the use of them, as well as pharmaceutical N compositions containing at least one of them as pharmaceutically active agent(s) together with pharmaceutically acceptable carrier, excipient and/or diluents, especially for the prevention and/or treatment of acute neurogenic inflammation and/or neuropathic hyperalgesia. Said 4-phenetylamino-7H-pyrrolo[2,3-d]pyrimidine compounds have been identified as new drug candidates for the prevention and/or treatment of acute neurogenic inflammation and/or neuropathic hyperalgesia.