专利检索 ap:("PFIZER") AND inv:"BRIGHT G" 第 1 页

1.

发明授权
6 - (alpha - (aryl substituted)acylamino-acylamino)penicillanic acidsand derivatives thereof 失效
标题翻译： 6 - （ALPHA - （ARYL取代）ACYLAMINO-ACYLAMINO）苯丙胺酸及其衍生物

公开(公告)号：US3770722A

公开(公告)日：1973-11-06

申请号：US3770722D

申请日：1971-10-04

申请人： PFIZER

发明人： BRIGHT G , HAMANAKA E

IPC分类号： C07D499/00 , C07D499/64 , C07D99/16

CPC分类号： C07D499/00

摘要： A NOVEL SERIES OF ANTIBACTERIAL AGENTS; NAMELY, 6-(A(ARYL SUBSTITUTED)ACYLAMINOACYLAMINO)PENICILLANIC ACIDS OF THE FORMULA

6-(Z-NH-CH2-CO-NH-),2-(HOOC-),3,3-DI(CH3-)PENAM

THE NON-TOXIC SALTS, ESTERS AND AMIDES THEREOF WHEREIN Z IS RR1CH-CO-; R IS PHENYL, SUBSTITUTED PHENYL OR THIENYL; R1 IS HYDROGEN OR COOH; AND INTERMEDIATES THEREFOR OF THE ABOVE FORMULA WHEREIN Z IS HYDROGEN.

2.

发明授权
6 - (alpha(aryl substituted)-omega-amino-omega-carboxy acylamino)penicillanic acids and derivatives thereof 失效
标题翻译： 6 - （ALPHA（ARYL取代） - 氨基 - 氨基 - 羧基 - 氨基亚氨基）苯胺酸及其衍生物

公开(公告)号：US3761466A

公开(公告)日：1973-09-25

申请号：US3761466D

申请日：1971-07-09

申请人： PFIZER

发明人： BRIGHT G

IPC分类号： C07D499/00 , C07D499/46 , C07D499/48 , C07D99/16

CPC分类号： C07D499/00 , Y02P20/55

摘要： A NOVEL SERIES OF ANTIBACTERIAL AGENTS; NAMELY, 6-(A(ARYL SUBSTITUTED)-W-AMINO-W-CARBOXYACYLAMINO) PENICILLANIC ACIDS OF THE FORMULA:

6-(R3-OOC-CH(-NH-R4)-(CH2)N-CH(-R1)-CO-NH-),2-(R2-OOC-),

3,3-DI(CH3-)PENAM

AND THE NON-TOXIC, CATIONIC SALTS THEREOF WHEREIN: R1 IS THIENYL, PHENYL AND SUBSTITUTED PHENYL; R2 IS HYDROGEN AND ACYLOXY LOWER ALKYL; R3 IS HYDROGEN, LOWER ALKYL AND BENZYL; R4 IS SELECTED FROM THE GROUP CONSISTING OF HYDROGEN AND CARBOBENZOXY; AND N IS 0 OR 1.