公开(公告)号：US11633676B2

公开(公告)日：2023-04-25

申请号：US16608842

申请日：2018-06-01

Applicant: PHASE DIAGNOSTICS, INC.

Inventor： Yin To Chiu ,  Brian Sangwoo Lee ,  Garrett Lee Mosley ,  Beatrice S. Lim

IPC: B01D17/02 ,  C07K1/14 ,  C07K1/36 ,  B01D15/00 ,  B01J20/32 ,  G01N1/40 ,  B01D19/00 ,  B01D11/04 ,  B01D17/12

Abstract: The present invention relates to a method and/or device for improving the separation behaviors and performance of aqueous two-phase system (ATPS) for the isolation and/or concentration of one or more target analytes from a sample. In one embodiment, the present method and device comprise ATPS components within a porous material and one or more phase separation behavior modifying agents that improve the separation behavior and performance characteristics of ATPS, including but not limited to the increasing the stability or reducing fluctuations of ATPS thought the adjustment of total volume of a sample solution that undergoes phase separation, volume ratio of the two phases of the ATPS, fluid flow rates, and concentrations of ATPS components.

公开(公告)号：US20230211257A1

公开(公告)日：2023-07-06

申请号：US18182372

申请日：2023-03-13

Applicant: PHASE DIAGNOSTICS, INC.

Inventor： Yin To Chiu ,  Brian Sangwoo Lee ,  Garrett Lee Mosley ,  Beatrice S. Lim

IPC: G01N1/40

CPC classification number: G01N1/405 ,  G01N2001/4061

Abstract: The present invention relates to a method and/or device for improving the separation behaviors and performance of aqueous two-phase system (ATPS) for the isolation and/or concentration of one or more target analytes from a sample. In one embodiment, the present method and device comprise ATPS components within a porous material and one or more phase separation behavior modifying agents that improve the separation behavior and performance characteristics of ATPS, including but not limited to the increasing the stability or reducing fluctuations of ATPS thought the adjustment of total volume of a sample solution that undergoes phase separation, volume ratio of the two phases of the ATPS, fluid flow rates, and concentrations of ATPS components.

公开(公告)号：US11938419B2

公开(公告)日：2024-03-26

申请号：US18182372

申请日：2023-03-13

Applicant: PHASE DIAGNOSTICS, INC.

Inventor： Yin To Chiu ,  Brian Sangwoo Lee ,  Garrett Lee Mosley ,  Beatrice S. Lim

IPC: B01D11/04 ,  B01D15/00 ,  B01D17/02 ,  B01D17/12 ,  B01D19/00 ,  B01J20/32 ,  C07K1/14 ,  C07K1/36 ,  G01N1/40

CPC classification number: B01D17/0214 ,  B01D11/0492 ,  B01D15/00 ,  B01D17/02 ,  B01D17/0202 ,  B01D17/12 ,  B01D19/0057 ,  B01J20/3208 ,  B01J20/3274 ,  B01J20/3287 ,  B01J20/3289 ,  C07K1/145 ,  C07K1/36 ,  G01N1/405 ,  G01N2001/4061

Abstract: The present invention relates to a method and/or device for improving the separation behaviors and performance of aqueous two-phase system (ATPS) for the isolation and/or concentration of one or more target analytes from a sample. In one embodiment, the present method and device comprise ATPS components within a porous material and one or more phase separation behavior modifying agents that improve the separation behavior and performance characteristics of ATPS, including but not limited to the increasing the stability or reducing fluctuations of ATPS thought the adjustment of total volume of a sample solution that undergoes phase separation, volume ratio of the two phases of the ATPS, fluid flow rates, and concentrations of ATPS components.