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公开(公告)号：US20190350940A1
公开(公告)日：2019-11-21
申请号：US16413719
申请日：2019-05-16
发明人： Rossitza G. Alargova , Mark T. Bilodeau , Richard Wooster , Benoît Moreau , Kerry Whalen , J. Michael Ramstack , Danielle N. Rockwood , Patrick Lim Soo , Sukhjeet Singh , Tsun P. Au Yeung , Charles-Andre Lemelin , Linda M. Custer
IPC分类号： A61K31/555 , A61K31/4015 , A61K47/26 , A61P35/00 , A61K9/00 , A61K9/08 , A61K47/02
摘要： The present teachings relate to compounds and compositions for treatment of cancers. In some embodiments, the composition comprises a platinum (IV) complex having at least one reacting group for reacting with a functional group on a protein.
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公开(公告)号：US20180243318A1
公开(公告)日：2018-08-30
申请号：US15737064
申请日：2016-06-22
发明人： Rossitza G. Alargova , Mark T. Bilodeau , Richard Wooster , Benoît Moreau , Kerry Whalen , J. Michael Ramstack , Danielle N. Rockwood , Patrick Lim Soo , Sukhjeet Singh , Tsun P. Au Yeung , Charles-Andre Lemelin , Linda M. Custer
IPC分类号： A61K31/555 , A61K9/08 , A61K47/26 , A61P35/00
CPC分类号： A61K31/555 , A61K9/0019 , A61K9/08 , A61K31/4015 , A61K47/02 , A61K47/26 , A61P35/00
摘要： The present teachings relate to compounds and compositions for treatment of cancers. In some embodiments, the composition comprises a platinum (IV) complex having at least one reacting group for reacting with a functional group on a protein.
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公开(公告)号：US10342801B2
公开(公告)日：2019-07-09
申请号：US15737064
申请日：2016-06-22
发明人： Rossitza G. Alargova , Mark T. Bilodeau , Richard Wooster , Benoît Moreau , Kerry Whalen , J. Michael Ramstack , Danielle N. Rockwood , Patrick Lim Soo , Sukhjeet Singh , Tsun P. Au Yeung , Charles-Andre Lemelin , Linda M. Custer
IPC分类号： A61K31/555 , A61K9/00 , A61K47/02 , A61K47/26 , A61P35/00 , A61K9/08 , A61K31/4015
摘要： The present teachings relate to compounds and compositions for treatment of cancers. In some embodiments, the composition comprises a platinum (IV) complex having at least one reacting group for reacting with a functional group on a protein.
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公开(公告)号：US09937187B2
公开(公告)日：2018-04-10
申请号：US15179701
申请日：2016-06-10
发明人： Mark T. Bilodeau , Benoît Moreau , Adam H. Brockman , Kristan Meetze , Kerry Whalen , Richard Wooster , Rossitza G. Alargova
IPC分类号： C07F15/00 , A61K31/555 , A61K33/24 , A61K31/282
CPC分类号： A61K31/555 , A61K31/282 , A61K33/24 , C07F15/00
摘要： The present teachings relate to compounds and compositions for treatment of cancers. In some embodiments, the composition comprises a platinum (IV) complex having at least one reacting group for reacting with a functional group on a protein, engineered protein, antibody, antibody fragment, peptide, agonist, antagonist, aptamer or ligand which may be capable of recognizing a selected target cell population, and/or derivatives/analogs/mimics thereof.
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公开(公告)号：US20180008614A1
公开(公告)日：2018-01-11
申请号：US15711041
申请日：2017-09-21
发明人： Mark T. Bilodeau , Benoît Moreau , Adam H. Brockman , Kristan Meetze , Kerry Whalen , Richard Wooster , Rossitza G. Alargova
IPC分类号： A61K31/555 , A61K31/282 , A61K33/24 , C07F15/00
CPC分类号： A61K31/555 , A61K31/282 , A61K33/24 , C07F15/00
摘要： The present teachings relate to compounds and compositions for treatment of cancers. In some embodiments, the composition comprises a platinum (IV) complex having at least one reacting group for reacting with a functional group on a protein, engineered protein, antibody, antibody fragment, peptide, agonist, antagonist, aptamer or ligand which may be capable of recognizing a selected target cell population, and/or derivatives/analogs/mimics thereof.
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公开(公告)号：US10322137B2
公开(公告)日：2019-06-18
申请号：US15711041
申请日：2017-09-21
发明人： Mark T. Bilodeau , Benoit Moreau , Adam H. Brockman , Kristan Meetze , Kerry Whalen , Richard Wooster , Rossitza G. Alargova
IPC分类号： C07F15/00 , A61K31/555 , A61K31/282 , A61K33/24
摘要： The present teachings relate to compounds and compositions for treatment of cancers. In some embodiments, the composition comprises a platinum (IV) complex having at least one reacting group for reacting with a functional group on a protein, engineered protein, antibody, antibody fragment, peptide, agonist, antagonist, aptamer or ligand which may be capable of recognizing a selected target cell population, and/or derivatives/analogs/mimics thereof.
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公开(公告)号：US20180186823A1
公开(公告)日：2018-07-05
申请号：US15737073
申请日：2016-06-22
发明人： Sudhakar Kadiyala , Benoît Moreau , Mark T. Bilodeau , Kerry Whalen , Sukhjeet Singh , Richard Wooster , Charles-Andre Lemelin
CPC分类号： C07F15/0093 , A61K31/282 , A61K31/40 , A61K31/555 , A61K33/24 , A61K38/38 , A61K45/06 , A61K47/545 , A61K47/643 , A61P35/00 , A61K2300/00
摘要： The present teachings relate to compounds and compositions comprising a platinum (IV) complex having at least one reacting group for reacting with a functional group on a protein, engineered protein, antibody, antibody fragment, peptide, agonist, antagonist, aptamer or any moiety which may be capable of recognizing a selected target cell population, and/or derivatives/analogs/mimics thereof. The platinum (IV) complex may comprise at least one active agent.
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