公开(公告)号：US20170339930A1

公开(公告)日：2017-11-30

申请号：US15596049

申请日：2017-05-16

Applicant: POSTECH ACADEMY-INDUSTRY FOUNDATION

Inventor： SEUNG-JAE LEE ,  MURAT ARTAN ,  DAE-EUN JEONG

IPC: A01K67/033

CPC classification number: A01K67/0336 ,  A01K2207/30 ,  A01K2217/052 ,  A01K2217/072 ,  A01K2227/703 ,  A01K2267/03 ,  A01K2267/0393

Abstract: The present disclosure relates to transgenic Caenorhabditis elegans including, in sensory neurons, Channelrhodopsin 2 (ChR2)::Green Fluorescence Protein (GFP) DNA in which the ChR2 gene and the GFP gene are linked, a method of producing the same, a method of regulating the lifespan thereof, and a method of screening an aging regulation candidate by using the same. The present disclosure may also provide an animal model for research into prevention/treatment of aging-related diseases by regulating the lifespan of an animal on a subject level and a method of screening a drug candidate for prevention/treatment of aging-related diseases.