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公开(公告)号：US11883630B2
公开(公告)日：2024-01-30
申请号：US16314737
申请日：2017-07-06
CPC分类号： A61M5/1723 , G16H20/17 , A61M2205/52 , A61M2230/201
摘要： The development of artificial pancreas (AP) technology for deployment in low-energy, embedded devices is contingent upon selecting an efficient control algorithm for regulating glucose in people with type 1 diabetes mellitus (T1DM). The energy consumption of the AP can be lowered by reducing updates of the control model: the number of times the decisionmaking algorithm is invoked to compute an appropriate insulin dose.
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公开(公告)号：US12128212B2
公开(公告)日：2024-10-29
申请号：US16973628
申请日：2019-06-19
发明人： Eyal Dassau , Francis J. Doyle, III , Dawei Shi
IPC分类号： A61M5/172 , G16H10/60 , G16H20/17 , G16H40/40 , G16H40/67 , G16H50/20 , G16H50/30 , G16H70/40 , A61M5/142
CPC分类号： A61M5/1723 , G16H10/60 , G16H20/17 , G16H40/40 , G16H40/67 , G16H50/20 , G16H50/30 , G16H70/40 , A61M2005/14208 , A61M2230/201
摘要： A system for the delivery of insulin to a patient is provided. The systems and methods disclose include an insulin delivery device configured to deliver insulin to a patient in response to control signals. The system also includes a controller programmed to receive the sensor glucose measurement signal from the glucose sensor. The sensor glucose measurement signal received indicates a concentration of the real time glucose concentration in a bloodstream. The controller is further configured to enact an impeding glycemia protocol based on a zone model predictive control (MPC) algorithm in response to the real time glucose concentration. The impeding glycemia protocol includes in determining a relationship between predicted glucose concentrations, a rate of change of the predicted glucose concentrations, and a set of control parameters that determine insulin doses above and below a patient-specific basal rate.
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