公开(公告)号：US11406625B2

公开(公告)日：2022-08-09

申请号：US16789564

申请日：2020-02-13

Applicant: PRILENIA NEUROTHERAPEUTICS LTD.

Inventor： Michal Geva ,  Ralph Laufer ,  Michael Hayden ,  Neta Zach

IPC: A61K31/44 ,  A61P25/14 ,  A61K9/00 ,  A61K31/185 ,  A61K31/222 ,  A61K31/4152 ,  A61K31/426 ,  A61K31/4748 ,  A61K31/49

Abstract: Provided herein is a method for treating a human subject afflicted with ALS by administering to the subject a therapeutically effective amount of pridopidine as monotherapy or together with riluzole, edaravone, combination of dextromethorphan/quinidine, sodium phenylbutyrate (PB), tauroursodeoxycholic acid or combination of sodium phenylbutyrate (PB)/tauroursodeoxycholic acid (i.e. AMX0035) as combination or add-on therapy.