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公开(公告)号：US11406625B2
公开(公告)日：2022-08-09
申请号：US16789564
申请日：2020-02-13
Applicant: PRILENIA NEUROTHERAPEUTICS LTD.
Inventor： Michal Geva , Ralph Laufer , Michael Hayden , Neta Zach
IPC: A61K31/44 , A61P25/14 , A61K9/00 , A61K31/185 , A61K31/222 , A61K31/4152 , A61K31/426 , A61K31/4748 , A61K31/49
Abstract: Provided herein is a method for treating a human subject afflicted with ALS by administering to the subject a therapeutically effective amount of pridopidine as monotherapy or together with riluzole, edaravone, combination of dextromethorphan/quinidine, sodium phenylbutyrate (PB), tauroursodeoxycholic acid or combination of sodium phenylbutyrate (PB)/tauroursodeoxycholic acid (i.e. AMX0035) as combination or add-on therapy.
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公开(公告)号：US12036213B2
公开(公告)日：2024-07-16
申请号：US17315667
申请日：2021-05-10
Applicant: PRILENIA NEUROTHERAPEUTICS LTD.
Inventor： Michal Geva , Aric Orbach , Michael Hayden
IPC: A61K31/451 , A61K9/00 , A61K45/06 , A61P25/14 , A61P25/16 , A61K31/198
CPC classification number: A61K31/451 , A61K9/0053 , A61K45/06 , A61P25/14 , A61P25/16 , A61K31/198
Abstract: The invention provides a method of treating a subject afflicted with a drug-induced movement disorder including levodopa-induced dyskinesia comprising periodically administering to the subject in need thereof an amount of pridopidine or pharmaceutically acceptable salt thereof effective to treat the subject. The invention further provides a method of treating a subject at risk of developing a drug-induced movement disorder, including levodopa-induced dyskinesia.
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公开(公告)号：US10603311B2
公开(公告)日：2020-03-31
申请号：US15052368
申请日：2016-02-24
Applicant: PRILENIA NEUROTHERAPEUTICS LTD.
Inventor： Michal Geva , Ilya Bezprozvanny , Merav Bassan , Michael Hayden
IPC: A61K31/451 , C07D211/24 , C07D211/52 , C07D211/42
Abstract: This invention provides a method of improving cognitive function in a subject comprising periodically administering to the subject an amount of pridopidine or a pharmaceutically acceptable salt thereof effective to improve a cognitive function in the subject.The invention also provides a method of treating a subject afflicted with Alzheimer's disease, comprising periodically administering to the subject a pharmaceutical composition comprising an amount of pridopidine or a pharmaceutically acceptable salt thereof effective to treat the subject.
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公开(公告)号：US11738012B2
公开(公告)日：2023-08-29
申请号：US16078929
申请日：2017-02-24
Applicant: PRILENIA NEUROTHERAPEUTICS LTD.
Inventor： Hermann Kurt Russ , Michal Geva , Ralph Laufer , Aric Orbach
IPC: A61K31/451 , A61K45/06 , A61P27/02 , A61P27/06
CPC classification number: A61K31/451 , A61K45/06 , A61P27/02 , A61P27/06
Abstract: The subject invention provides a method of treating a subject afflicted with a neurodegenerative eye disease comprising administering to the subject an amount of pridopidine effective to treat the subject.
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公开(公告)号：US11000519B2
公开(公告)日：2021-05-11
申请号：US16436947
申请日：2019-06-11
Applicant: PRILENIA NEUROTHERAPEUTICS LTD.
Inventor： Michal Geva , Aric Orbach , Michael Hayden
IPC: A61K31/445 , A61K31/451 , A61P25/14 , A61K45/06 , A61P25/16 , A61K9/00 , A61K31/198
Abstract: The invention provides a method of treating a subject afflicted with a drug-induced movement disorder including levodopa-induced dyskinesia comprising periodically administering to the subject in need thereof an amount of pridopidine effective to treat the subject. The invention further provides a method of treating a subject at risk of developing a drug-induced movement disorder, including levodopa-induced dyskinesia. The invention also provides pharmaceutical compositions suitable for carrying out these methods and packages containing such pharmaceutical compositions.
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Patent Agency Ranking
公开(公告)号：US20200093813A1
公开(公告)日：2020-03-26
申请号：US16591875
申请日：2019-10-03
Inventor： Michal Geva , Ilya Bezprozvanny , Merav Bassan , Michael Hayden
IPC: A61K31/451 , A61P25/28 , A61P25/08
Abstract: This invention provides a method of improving cognitive function in a subject comprising periodically administering to the subject an amount of pridopidine or a pharmaceutically acceptable salt thereof effective to improve a cognitive function in the subject.The invention also provides a method of treating a subject afflicted with Alzheimer's disease, comprising periodically administering to the subject a pharmaceutical composition comprising an amount of pridopidine or a pharmaceutically acceptable salt thereof effective to treat the subject.
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公开(公告)号：US20220062255A1
公开(公告)日：2022-03-03
申请号：US17513239
申请日：2021-10-28
Applicant: PRILENIA NEUROTHERAPEUTICS LTD.
Inventor： Michal Geva , Hermann Kurt Russ , Ralph Laufer , Aric Orbach
IPC: A61K31/451 , A61P27/06 , A61K9/00
Abstract: This application provides a method of treating a subject afflicted with a neurodegenerative eye disease comprising administering to the subject an amount of pridopidine effective to treat the subject, pharmaceutical composition and uses and applications thereof.
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公开(公告)号：US20210052560A1
公开(公告)日：2021-02-25
申请号：US17019346
申请日：2020-09-13
Applicant: PRILENIA NEUROTHERAPEUTICS LTD.
Inventor： Michael Hayden , Michal Geva
Abstract: This invention provides a method of maintaining functional capacity, improving functional capacity, or lessening the decline of functional capacity in a human patient comprising periodically orally administering to the patient a pharmaceutical composition comprising pridopidine such that a dose of 90 mg of pridopidine is administered to the patient per day, so as to thereby maintain functional capacity, improve functional capacity, or lessen the decline of functional capacity in the human patient.
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公开(公告)号：US12102627B2
公开(公告)日：2024-10-01
申请号：US16952123
申请日：2020-11-19
Applicant: PRILENIA NEUROTHERAPEUTICS LTD.
Inventor： Michal Geva , Ralph Laufer , Michael Hayden
IPC: A61K31/451 , A61K9/00 , A61P25/14
CPC classification number: A61K31/451 , A61K9/0019 , A61K9/0053 , A61P25/14
Abstract: The subject invention provides a method for treating a subject afflicted with Rett syndrome comprising administering to the subject an effective amount of pridopidine so as to thereby treat the subject.
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公开(公告)号：US11471449B2
公开(公告)日：2022-10-18
申请号：US16591875
申请日：2019-10-03
Inventor： Michal Geva , Ilya Bezprozvanny , Merav Bassan , Michael Hayden
IPC: A61P25/08 , A61K31/451 , A61P25/28 , A61K45/06
Abstract: This invention provides a method of improving cognitive function in a subject comprising periodically administering to the subject an amount of pridopidine or a pharmaceutically acceptable salt thereof effective to improve a cognitive function in the subject.
The invention also provides a method of treating a subject afflicted with Alzheimer's disease, comprising periodically administering to the subject a pharmaceutical composition comprising an amount of pridopidine or a pharmaceutically acceptable salt thereof effective to treat the subject.
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