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公开(公告)号：US20210124115A1
公开(公告)日：2021-04-29
申请号：US17012966
申请日：2020-09-04
发明人： Ravi SAXENA , Michael Tzu RU , Takashi Whitney ORIMOTO , Annette GROT , Mathieu FOQUET , Hou-Pu CHOU
IPC分类号： G02B6/12 , G02B6/136 , B29D17/00 , G02B6/02 , B29D11/00 , C12Q1/6869 , G01N21/64 , G02B5/18 , G02B6/124
摘要： Arrays of integrated analytical devices and their methods for production are provided. The arrays are useful in the analysis of highly multiplexed optical reactions in large numbers at high densities, including biochemical reactions, such as nucleic acid sequencing reactions. The integrated devices allow the highly sensitive discrimination of optical signals using features such as spectra, amplitude, and time resolution, or combinations thereof. The arrays and methods of the invention make use of silicon chip fabrication and manufacturing techniques developed for the electronics industry and highly suited for miniaturization and high throughput.
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公开(公告)号：US20170322156A1
公开(公告)日：2017-11-09
申请号：US15600668
申请日：2017-05-19
发明人： Ravi SAXENA , Michael Tzu RU , Takashi Whitney ORIMOTO , Annette GROT , Mathieu FOQUET , Hou-Pu CHOU
IPC分类号： G01N21/64 , G02B6/02 , G02B6/12 , G02B6/124 , G02B6/136 , G02B5/18 , B29D11/00 , C12Q1/68 , B29D17/00 , B29L11/00
CPC分类号： G02B6/12004 , B29D11/0073 , B29D17/007 , B29L2011/005 , B29L2011/0066 , B29L2011/0075 , C12Q1/6869 , G01N21/6454 , G01N21/648 , G01N2021/6478 , G01N2201/0873 , G02B5/189 , G02B6/02123 , G02B6/124 , G02B6/136 , G02B2006/12038 , G02B2006/12109
摘要： Arrays of integrated analytical devices and their methods for production are provided. The arrays are useful in the analysis of highly multiplexed optical reactions in large numbers at high densities, including biochemical reactions, such as nucleic acid sequencing reactions. The integrated devices allow the highly sensitive discrimination of optical signals using features such as spectra, amplitude, and time resolution, or combinations thereof. The arrays and methods of the invention make use of silicon chip fabrication and manufacturing techniques developed for the electronics industry and highly suited for miniaturization and high throughput.
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公开(公告)号：US20160334334A1
公开(公告)日：2016-11-17
申请号：US15158756
申请日：2016-05-19
发明人： Ravi SAXENA , Michael Tzu RU , Takashi Whitney ORIMOTO , Annette GROT , Mathieu FOQUET , Hou-Pu CHOU
CPC分类号： G02B6/12004 , B29D11/0073 , B29D17/007 , B29L2011/005 , B29L2011/0066 , B29L2011/0075 , C12Q1/6869 , G01N21/6454 , G01N21/648 , G01N2021/6478 , G01N2201/0873 , G02B5/189 , G02B6/02123 , G02B6/124 , G02B6/136 , G02B2006/12038 , G02B2006/12109
摘要： Arrays of integrated analytical devices and their methods for production are provided. The arrays are useful in the analysis of highly multiplexed optical reactions in large numbers at high densities, including biochemical reactions, such as nucleic acid sequencing reactions. The integrated devices allow the highly sensitive discrimination of optical signals using features such as spectra, amplitude, and time resolution, or combinations thereof. The arrays and methods of the invention make use of silicon chip fabrication and manufacturing techniques developed for the electronics industry and highly suited for miniaturization and high throughput.
摘要翻译： 提供了集成分析设备阵列及其生产方法。 阵列可用于高密度高分复用的光学反应，包括生化反应，如核酸测序反应。 集成器件允许使用诸如光谱，幅度和时间分辨率之类的特征或其组合来对光信号进行高灵敏度鉴别。 本发明的阵列和方法利用为电子工业开发的硅芯片制造和制造技术，并且非常适合于小型化和高吞吐量。
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公开(公告)号：US20200142127A1
公开(公告)日：2020-05-07
申请号：US16430134
申请日：2019-06-03
发明人： Ravi SAXENA , Michael Tzu RU , Takashi Whitney ORIMOTO , Annette GROT , Mathieu FOQUET , Hou-Pu CHOU
IPC分类号： G02B6/12 , G02B6/136 , B29D17/00 , G02B6/02 , B29D11/00 , C12Q1/6869 , G01N21/64 , G02B5/18 , G02B6/124
摘要： Arrays of integrated analytical devices and their methods for production are provided. The arrays are useful in the analysis of highly multiplexed optical reactions in large numbers at high densities, including biochemical reactions, such as nucleic acid sequencing reactions. The integrated devices allow the highly sensitive discrimination of optical signals using features such as spectra, amplitude, and time resolution, or combinations thereof. The arrays and methods of the invention make use of silicon chip fabrication and manufacturing techniques developed for the electronics industry and highly suited for miniaturization and high throughput.
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公开(公告)号：US20180239087A1
公开(公告)日：2018-08-23
申请号：US15953792
申请日：2018-04-16
发明人： Ravi SAXENA , Michael Tzu RU , Takashi Whitney ORIMOTO , Annette GROT , Mathieu FOQUET , Hou-Pu CHOU
IPC分类号： G02B6/12 , G02B6/124 , B29D11/00 , G01N21/64 , B29D17/00 , G02B5/18 , G02B6/136 , C12Q1/6869 , G02B6/02 , B29L11/00
CPC分类号： G02B6/12004 , B29D11/0073 , B29D17/007 , B29L2011/005 , B29L2011/0066 , B29L2011/0075 , C12Q1/6869 , G01N21/6454 , G01N21/648 , G01N2021/6478 , G01N2201/0873 , G02B5/189 , G02B6/02123 , G02B6/124 , G02B6/136 , G02B2006/12038 , G02B2006/12109
摘要： Arrays of integrated analytical devices and their methods for production are provided. The arrays are useful in the analysis of highly multiplexed optical reactions in large numbers at high densities, including biochemical reactions, such as nucleic acid sequencing reactions. The integrated devices allow the highly sensitive discrimination of optical signals using features such as spectra, amplitude, and time resolution, or combinations thereof. The arrays and methods of the invention make use of silicon chip fabrication and manufacturing techniques developed for the electronics industry and highly suited for miniaturization and high throughput.
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