公开(公告)号：US20230270780A1

公开(公告)日：2023-08-31

申请号：US18044559

申请日：2021-08-10

申请人： Paean Biotechnology Inc.

发明人： Young-Cheol KANG ,  Kyuboem HAN ,  Sang-Min LIM ,  Hahnsun JUNG ,  Hye Jeong HWANG ,  Junyoung SON

IPC分类号： A61K35/12 ,  A61K9/00 ,  A61K9/08 ,  A61K47/18 ,  A61K47/26

CPC分类号： A61K35/12 ,  A61K9/0019 ,  A61K9/08 ,  A61K47/183 ,  A61K47/26

摘要： Provided is a composition for injection containing isolated mitochondria. More specifically, provided is a liquid composition for injection containing glycine, saccharide, buffer, and mitochondria, and a pharmaceutical composition comprising the liquid composition for injection as an active ingredient. The liquid composition for injection according to the present disclosure is capable of securing the safety of a mitochondrial therapeutic and maintaining the activity of mitochondria, by enhancing the stability of mitochondria for prevention or treatment of mitochondria-related diseases and preventing and inhibiting formation of blood clots in the blood of a subject who is administered with the same. Accordingly, the pharmaceutical composition according to the present disclosure may solve the aggregation that may occur when mitochondria are administered in the body and thus enables to safely and effectively inject mitochondria into the body to be used for the purpose of preventing and treating various diseases caused by mitochondrial dysfunction.