Ligand sensing fluorescent acetylcholinesterase for detection of organophosphate activity
    1.
    发明授权
    Ligand sensing fluorescent acetylcholinesterase for detection of organophosphate activity 有权
    配体感测荧光乙酰胆碱酯酶用于检测有机磷酸酯活性

    公开(公告)号:US08642273B2

    公开(公告)日:2014-02-04

    申请号:US10469731

    申请日:2003-04-16

    IPC分类号: C12N9/18

    CPC分类号: C12N9/18

    摘要: Disclosed are methods for the preparation and use of labeled AChE and labeled AChE inhibitory conjugate compositions for detecting accumulation of toxic materials such as organophosphates, insecticides, and other nerve agents. Also disclosed are methods for the use of labeled AChE and labeled AChE inhibitory conjugate compositions in a variety of areas, including the detecting of toxic materials in biological samples, in the area of food and water analysis, in environmental monitoring, and in industrial settings.

    摘要翻译: 公开了用于制备和使用标记的AChE和标记的AChE抑制性缀合物组合物的方法,用于检测有毒物质如有机磷酸盐,杀虫剂和其它神经毒剂的积累。 还公开了在各种领域中使用标记的AChE和标记的AChE抑制性缀合物组合物的方法,包括在食品和水分析领域,环境监测和工业环境中检测生物样品中的有毒物质。