公开(公告)号：US20190077836A1

公开(公告)日：2019-03-14

申请号：US16054231

申请日：2018-08-03

Applicant: Panasonic Intellectual Property Management Co., Ltd.

Inventor： EMINA IKEUCHI

IPC: C07K14/11 ,  G01N33/543 ,  G01N33/533

Abstract: The present invention is an antibody including an amino acid sequence, wherein the amino acid sequence includes, in an N- to C-direction, the following structural domains: N-FR1-CDR1-FR2-CDR2-FR3-CDR3-FR4-C wherein FR denotes a framework region amino acid sequence and CDR denotes a complementary determining region amino acid sequence; the CDR1 includes an amino acid sequence represented by SEQ ID NO: 1; the CDR2 includes an amino acid sequence represented by SEQ ID NO: 2; the CDR3 includes an amino acid sequence represented by SEQ ID NO: 3; and the antibody is capable of binding to an intranuclear protein of an influenza virus.

公开(公告)号：US20200291098A1

公开(公告)日：2020-09-17

申请号：US16742036

申请日：2020-01-14

Applicant: Panasonic Intellectual Property Management Co., Ltd.

Inventor： EMINA IKEUCHI

IPC: C07K16/10 ,  G01N33/543 ,  G01N33/569 ,  G01N21/75

Abstract: The present invention is an antibody including an amino acid sequence, wherein the amino acid sequence includes, in an N- to C-direction, the following structural domains: N-FR1-CDR1-FR2-CDR2-FR3-CDR3-FR4-C wherein FR denotes a framework region amino acid sequence and CDR denotes a complementary determining region amino acid sequence; the CDR1 includes an amino acid sequence represented by GFTFSNY (SEQ ID NO: 1): the CDR2 includes an amino acid sequence represented by NSGGTG (SEQ ID NO: 2); and the CDR3 includes an amino acid sequence represented by RVDGRVLSTIVVSYDY (SEQ ID NO: 3). The antibody is capable of binding to an intranuclear protein of an influenza virus.

公开(公告)号：US20200025759A1

公开(公告)日：2020-01-23

申请号：US16431769

申请日：2019-06-05

Applicant: Panasonic Intellectual Property Management Co., Ltd.

Inventor： EMINA IKEUCHI

IPC: G01N33/569 ,  C07K16/10

Abstract: The present invention is an antibody including an amino acid sequence, wherein the amino acid sequence includes, in an N- to C-direction, the following structural domains: N-FR1-CDR1-FR2-CDR2-FR3-CDR3-FR4-C wherein FR denotes a framework region amino acid sequence and CDR denotes a complementary determining region amino acid sequence; the CDR1 includes an amino acid sequence represented by SEQ ID NO: 1; the CDR2 includes an amino acid sequence represented by SEQ ID NO: 2; and the CDR3 includes an amino acid sequence represented by SEQ ID NO: 3. The antibody is capable of binding to an intranuclear protein of an influenza virus.

公开(公告)号：US20200166455A1

公开(公告)日：2020-05-28

申请号：US16747021

申请日：2020-01-20

Applicant: Panasonic Intellectual Property Management Co., Ltd.

Inventor： HIROTO YANAGAWA ,  MASAHIKO SHIOI ,  KAZUAKI NISHIO ,  EMINA IKEUCHI

IPC: G01N21/64 ,  G01N33/543 ,  G01N33/68

Abstract: The present disclosure provides a detection device capable of detecting a low concentration of an analyte with high sensitivity. The detection apparatus according to the present disclosure comprises a metal microstructure on which a first VHH antibody having a property of binding specifically to the analyte is immobilized and which generate surface plasmon by being irradiated with excitation light, an inlet through which a second VHH antibody and a sample that may contain an analyte are introduced, wherein the second VHH antibody has a property of binding specifically to the analyte and is labeled with a fluorescent substance, a light source for irradiating the metal microstructure to which the second VHH antibody and the sample have been introduced with the excitation light, and a detection unit for detecting the analyte on the basis of fluorescence generated from the fluorescent substance by the irradiation of the excitation light.

公开(公告)号：US20200165323A1

公开(公告)日：2020-05-28

申请号：US16726981

申请日：2019-12-26

Applicant: Panasonic Intellectual Property Management Co., Ltd.

Inventor： EMINA IKEUCHI

IPC: C07K16/10 ,  G01N33/569

Abstract: The present disclosure provides an antibody capable of binding to an intranuclear protein of an influenza virus and an application thereof. The present disclosure provides an antibody capable of recognizing a peptide consisting of the 205th-231st amino acid sequence in SEQ ID NO: 24.