公开(公告)号：US06402037B1

公开(公告)日：2002-06-11

申请号：US09441720

申请日：1999-11-16

申请人： Paras N. Prasad ,  Jayant D. Bhawalker ,  Ping Chin Cheng ,  Shan Jen Pan

发明人： Paras N. Prasad ,  Jayant D. Bhawalker ,  Ping Chin Cheng ,  Shan Jen Pan

IPC分类号： G06K1900

CPC分类号： A61K49/0021 ,  A61K41/008 ,  A61K49/0084 ,  G11C13/04

摘要： The present invention is directed to styryl dyes having the formula: wherein D is an electron donating group; Q is an electron acceptor selected from the group consisting of electron acceptors having the formulae: W is an electron accepting group, R3 is selected from the group consisting of substituted or unsubstituted alkyl or substituted or unsubstituted aryl moieties, n is an integer from 0 to 4, A, B, and C are substituents of their rings and are each independently selected from the group consisting of alkyl, alkoxy, hydroxyalkyl, sulfoalkyl, carboxyalkyl, and hydrogen, and Y is a counterion The present invention discloses media and methods for recording data. A three-dimensional matrix including a plurality of dye molecules, such a styryl dye molecule of the present invention, is provided. A first volume element in the matrix is exposed to actinic radiation for a duration and at an intensity effective to alter detectably a fraction between 0.3 and 0.7 of the dye molecules contained therein. The detectably altered dye molecules are substantially uniformly dispersed in the first volume element. The data storage methods and media of the present invention have approximately 1012 volume elements per square centimeter, and each of the volume elements can store a single bit, digital information of approximately 8 bits, or analog information. The data storage methods and media of the present invention are particularly useful for storing or archiving a series of two-dimensional black and white or color images, such as frames of a movie. Methods for reading data stored in the data storage media of the present invention using confocal microscopy are also disclosed.

摘要翻译： 本发明涉及具有下式的苯乙烯基染料：其中D是给电子基团; Q是选自下组的电子受体：具有下式的电子受体：W是电子接受基团，R 3选自 的取代或未取代的烷基或取代或未取代的芳基部分，n为0至4的整数，A，B和C为它们的环的取代基，并且各自独立地选自烷基，烷氧基，羟基烷基，磺基烷基， 羧基烷基和氢，Y是抗衡离子。本发明公开了用于记录数据的介质和方法。 提供了包含多个染料分子，如本发明的苯乙烯基染料分子的三维基质。 基质中的第一体积元素暴露于光化辐射持续时间，强度有效地改变其中所含的染料分子的0.3至0.7之间的分数。 可检测地改变的染料分子基本均匀地分散在第一容积元件中。 本发明的数据存储方法和介质具有每平方厘米大约1012体积的元素，并且每个体积元素可以存储大约8位的单位数字信息或模拟信息。 本发明的数据存储方法和媒体对于存储或归档一系列二维黑白图像或彩色图像（例如电影帧）特别有用。 还公开了使用共焦显微镜读取存储在本发明的数据存储介质中的数据的方法。

公开(公告)号：US5912257A

公开(公告)日：1999-06-15

申请号：US712143

申请日：1996-09-05

申请人： Paras N. Prasad ,  Jayant D. Bhawalkar ,  Guang S. He ,  Chan F. Zhao ,  Raz Gvishi ,  Gary E. Ruland ,  Jaroslaw Zieba ,  Ping Chin Cheng ,  Shan Jen Pan

发明人： Paras N. Prasad ,  Jayant D. Bhawalkar ,  Guang S. He ,  Chan F. Zhao ,  Raz Gvishi ,  Gary E. Ruland ,  Jaroslaw Zieba ,  Ping Chin Cheng ,  Shan Jen Pan

IPC分类号： G02B5/22 ,  A61K31/4425 ,  A61K41/00 ,  A61K49/00 ,  A61P31/12 ,  A61P35/00 ,  A61P43/00 ,  C07D213/36 ,  C07D213/38 ,  C07D213/89 ,  C08F2/46 ,  G02F1/361 ,  G03C1/73 ,  G11B7/004 ,  G11B7/244 ,  C07D213/90 ,  A61K31/44 ,  H01S3/14

CPC分类号： A61K49/0021 ,  A61K41/008 ,  A61K49/0084 ,  G11C13/04

摘要： Styryl dyes and compositions which exhibit superior two-photon absorption cross-sections and are useful in two-photon pumped cavity lasing, two-photon pumped upconversion lasing, optical power limiting, optical power stabilization, optical signal reshaping, and infrared beam detection and indication are disclosed. Also disclosed are multiphasic nanostructured composites which include a glass having pores, an optically active coating material on the pore surface, and a polymeric material in the pores. These composites are useful in producing multifunctional optical materials, such as broadly tunable lasers. Methods for killing cells and viruses using a photosensitizer and a two-photon upconverting dye are also described. These methods are especially useful to kill cells and viruses in biological materials, such as in photodynamic therapy of tumors and cancers or blood purification protocols. Media and methods for recording data in a three-dimensional matrix which includes a plurality of dye molecules is also described. The data storage methods and media have approximately 10.sup.12 volume elements per square centimeter, and each of the volume elements can store a single bit, digital information, or analog information. The data storage methods and media of the present invention are particularly useful for storing or archiving a series of two-dimensional black and white or color images, such as frames of a movie.

摘要翻译： 苯乙烯基染料和组合物，其表现出优异的双光子吸收横截面，并且可用于双光子泵浦腔激光，双光子泵浦上变频激光，光功率限制，光功率稳定，光信号整形和红外光束检测和指示 被披露。 还公开了多相纳米结构复合材料，其包括具有孔的玻璃，孔表面上的光学活性涂层材料和孔中的聚合材料。 这些复合材料可用于生产多功能光学材料，如广泛可调的激光器。 还描述了使用光敏剂和双光子上变频染料杀死细胞和病毒的方法。 这些方法对于杀死生物材料中的细胞和病毒特别有用，例如在肿瘤和癌症的光动力学治疗或血液净化方案中。 还描述了用于在包括多个染料分子的三维矩阵中记录数据的介质和方法。 数据存储方法和介质具有每平方厘米约1012体积的元件，并且每个体积元件可以存储单个位，数字信息或模拟信息。 本发明的数据存储方法和媒体对于存储或归档一系列二维黑白图像或彩色图像（例如电影帧）特别有用。