公开(公告)号：US20050002878A1

公开(公告)日：2005-01-06

申请号：US10491666

申请日：2002-10-03

Applicant: Pascal Lefrancois ,  Roger Navarro ,  Marlene Delaunois

Inventor： Pascal Lefrancois ,  Roger Navarro ,  Marlene Delaunois

IPC: A61K9/08 ,  A61K9/00 ,  A61K31/395 ,  A61K31/4436 ,  A61K31/573 ,  A61K47/10 ,  A61K47/12 ,  A61K47/14 ,  A61K47/18 ,  A61K47/32 ,  A61K47/38 ,  A61P17/00 ,  A61P17/06 ,  A61K7/04

CPC classification number: A61K9/0014 ,  A61K31/4436 ,  A61K47/10 ,  A61K47/14 ,  A61K47/32

Abstract: The invention concerns the use of tazarotene for preparing a nail varnish for treating and/or preventing psoriasis and nail varnish containing tazarotene and method for making same. More particularly, the invention concerns a nail varnish containing additionally to tazarotene a film-forming agent soluble or insoluble in polar solvents and physiologically acceptable solvents. Optionally it contains a penetration agent.

Abstract translation: 本发明涉及使用他扎罗汀来制备用于治疗和/或预防牛皮癣的指甲油和含有他扎罗汀的指甲油及其制备方法。 更具体地说，本发明涉及另外含有他扎罗汀的指甲油，可溶于或不溶于极性溶剂和生理学上可接受的溶剂的成膜剂。 可选地，它含有渗透剂。

公开(公告)号：US20110200544A1

公开(公告)日：2011-08-18

申请号：US13124796

申请日：2009-10-21

Applicant: Sophie Chesnoy ,  Marlène Delaunois ,  Héla Coubetergues ,  Pascal Lefrancois

Inventor： Sophie Chesnoy ,  Marlène Delaunois ,  Héla Coubetergues ,  Pascal Lefrancois

IPC: A61K31/17 ,  A61P17/12

CPC classification number: A61K9/0014 ,  A61K9/7015 ,  A61K31/17 ,  A61K47/32

Abstract: The invention relates to a film-forming solution comprising: −10 to 20% of urea, −5 to 15% of film-forming polymer, 45 to 65% of a polar solvent, 1 to 20% of a co-solvent, 0.01 to 5% of a plasticizer selected from the list consisting of diethyl phthalate, triethyl citrate, dibutyl sebacate, diethyl sebacate, dibutyl phthalate, acetyltriethyl citrate, and polyethylene glycols, and water up to 100% intended for treating ungual fungic infections and nail psoriasis.

Abstract translation: 本发明涉及一种成膜溶液，其包括：-10-20％的尿素，-5至15％的成膜聚合物，45至65％的极性溶剂，1至20％的共溶剂，0.01 至5％的增塑剂，其选自邻苯二甲酸二乙酯，柠檬酸三乙酯，癸二酸二乙酯，癸二酸二乙酯，邻苯二甲酸二丁酯，柠檬酸乙酰基三乙酯和聚乙二醇，以及用于治疗非法真菌感染和指甲银屑病的至多100％的水。