-
1.
公开(公告)号:US20060178305A1
公开(公告)日:2006-08-10
申请号:US11293761
申请日:2005-12-02
申请人: Patricia Vrignaud , Marielle Chiron-Blondel , Marie-Christine Bissery , Eric Furfine , Jocelyn Holash , Jesse Cedarbaum
发明人: Patricia Vrignaud , Marielle Chiron-Blondel , Marie-Christine Bissery , Eric Furfine , Jocelyn Holash , Jesse Cedarbaum
IPC分类号: A61K38/17 , A61K31/7072 , A61K31/513 , A61K31/525
CPC分类号: A61K31/513 , A61K31/505 , A61K31/519 , A61K31/7068 , A61K38/179 , A61K38/18 , A61K45/00 , A61K2300/00
摘要: This invention relates to antitumor combinations comprising a VEGF inhibitor combined with 5-fluorouracil or with a 5-fluoropyrimidine derivative that are therapeutically useful in the treatment of neoplastic diseases, and pharmaceutical compositions comprising such combinations.
-
2.Antitumor combinations containing a VEGF-inhibiting agent and 5FU or a derivative thereof 有权
标题翻译: 含有VEGF抑制剂和5FU或其衍生物的抗肿瘤组合公开(公告)号:US08388963B2
公开(公告)日:2013-03-05
申请号:US12508834
申请日:2009-07-24
申请人: Patricia Vrignaud , Marielle Chiron-Blondel , Marie-Christine Bissery , Eric Furfine , Jocelyn Holash , Jesse M. Cedarbaum
发明人: Patricia Vrignaud , Marielle Chiron-Blondel , Marie-Christine Bissery , Eric Furfine , Jocelyn Holash , Jesse M. Cedarbaum
CPC分类号: A61K31/513 , A61K31/505 , A61K31/519 , A61K31/7068 , A61K38/179 , A61K38/18 , A61K45/00 , A61K2300/00
摘要: This invention relates to antitumor combinations comprising a VEGF inhibitor combined with 5-fluorouracil or with a 5-fluoropyrimidine derivative that are therapeutically useful in the treatment of neoplastic diseases, and pharmaceutical compositions comprising such combinations.
摘要翻译: 本发明涉及包含与5-氟尿嘧啶组合的VEGF抑制剂或可用于治疗肿瘤性疾病的5-氟嘧啶衍生物的抗肿瘤组合物,以及包含这些组合的药物组合物。
-
公开(公告)号:US07851443B2
公开(公告)日:2010-12-14
申请号:US12142130
申请日:2008-06-19
IPC分类号: A61K38/00
CPC分类号: C07C237/04 , A61K31/05 , A61K31/136 , A61K31/167 , A61K38/179 , A61K39/00 , C07K2319/30 , A61K2300/00
摘要: This invention relates to therapeutic combinations comprising VEGF Trap and a stilbene derivative, and to methods for treatment of cancer comprising administration of such combinations.
摘要翻译: 本发明涉及包含VEGF Trap和二苯乙烯衍生物的治疗组合,以及涉及治疗癌症的方法,包括施用这种组合。
-
公开(公告)号:US06346543B1
公开(公告)日:2002-02-12
申请号:US09371838
申请日:1999-08-11
IPC分类号: A61K31335
CPC分类号: A61K31/335 , A61K31/337 , A61K38/191 , A61K38/20 , A61K38/212 , A61K38/215 , A61K45/06 , A61K2300/00
摘要: A method for treating abnormal cell proliferation in the brain by administering to a mammal in need thereof an effective amount of a taxoid derivative of formula (I) or a pharmaceutically acceptable salt or solvate thereof, wherein Z represents hydrogen or a radical of formula (II):
摘要翻译: 一种通过向有需要的哺乳动物施用有效量的式(I)的紫杉烷衍生物或其药学上可接受的盐或溶剂化物来治疗脑中异常细胞增殖的方法,其中Z表示氢或式(II)的基团 ):
-
5.ANTITUMOR COMBINATIONS CONTAINING ANTIBODIES RECOGNIZING SPECIFICALLY CD38 AND CYCLOPHOSPHAMIDE 审中-公开
标题翻译: 包含抗体的抗体组合识别特异性CD38和环磷酰胺公开(公告)号:US20110305690A1
公开(公告)日:2011-12-15
申请号:US13131389
申请日:2009-11-27
申请人: Pascale Lejeune , Patricia Vrignaud
发明人: Pascale Lejeune , Patricia Vrignaud
IPC分类号: A61K39/395 , A61P35/00
CPC分类号: A61K39/3955 , A61K31/00 , A61K31/664 , A61K31/675 , A61K39/395 , A61K2039/505 , A61K2300/00
摘要: Pharmaceutical composition comprising an antibody specifically recognizing CD38 and cyclophosphamide.
摘要翻译: 药物组合物,其包含特异性识别CD38和环磷酰胺的抗体。
-
6.ANTITUMOR COMBINATIONS CONTAINING ANTIBODIES RECOGNIZING SPECIFICALLY CD38 AND VINCRISTINE 有权
标题翻译: 包含抗体的抗体组合识别CD38和VINCRISTINE公开(公告)号:US20110293606A1
公开(公告)日:2011-12-01
申请号:US13130865
申请日:2009-11-27
申请人: Pascale Lejeune , Patricia Vrignaud
发明人: Pascale Lejeune , Patricia Vrignaud
IPC分类号: A61K39/395 , A61P35/00 , C07K16/28
CPC分类号: A61K31/475 , A61K31/00 , A61K39/395 , A61K2300/00
摘要: Pharmaceutical composition comprising an antibody specifically recognizing CD38 and vincristine.
摘要翻译: 药物组合物,其包含特异性识别CD38和长春新碱的抗体。
-
7.Antitumor combinations containing antibodies recognizing specifically CD38 and melphalan 有权
标题翻译: 含有特异性识别CD38和美法仑的抗体的抗肿瘤组合公开(公告)号:US09259406B2
公开(公告)日:2016-02-16
申请号:US13130862
申请日:2009-11-27
申请人: Pascale Lejeune , Patricia Vrignaud
发明人: Pascale Lejeune , Patricia Vrignaud
IPC分类号: A61K39/395 , A61K31/198
CPC分类号: A61K31/198 , A61K39/395 , A61K2300/00
摘要: Pharmaceutical composition comprising an antibody specifically recognizing CD38 and melphalan.
摘要翻译: 药物组合物包含特异性识别CD38和美法仑的抗体。
-
8.ANTITUMOR COMBINATIONS CONTAINING ANTIBODIES RECOGNIZING SPECIFICALLY CD38 AND CYTARABINE 审中-公开
标题翻译: 包含抗体的抗体组合识别特异性CD38和CYTARABABINE公开(公告)号:US20120093806A1
公开(公告)日:2012-04-19
申请号:US13130867
申请日:2009-11-27
申请人: Pascale Lejeune , Patricia Vrignaud
发明人: Pascale Lejeune , Patricia Vrignaud
IPC分类号: A61K39/395 , A61P35/00
CPC分类号: A61K31/7068 , A61K31/00 , A61K31/475 , A61K39/395 , A61K39/39558 , C07K16/2896 , C07K2317/24 , C07K2317/56 , C07K2317/565 , A61K2300/00
摘要: Pharmaceutical composition comprising an antibody specifically recognizing CD38 and cytarabine.
摘要翻译: 药物组合物包含特异性识别CD38和阿糖胞苷的抗体。
-
9.ANTITUMOR COMBINATIONS CONTAINING ANTIBODIES RECOGNIZING SPECIFICALLY CD38 AND MELPHALAN 有权
标题翻译: 含有特异性识别CD38和MELPHALAN抗体的抗肿瘤剂组合公开(公告)号:US20110274686A1
公开(公告)日:2011-11-10
申请号:US13130862
申请日:2009-11-27
申请人: Pascale Lejeune , Patricia Vrignaud
发明人: Pascale Lejeune , Patricia Vrignaud
IPC分类号: A61K39/395 , A61P35/00 , C07K16/28
CPC分类号: A61K31/198 , A61K39/395 , A61K2300/00
摘要: Pharmaceutical composition comprising an antibody specifically recognizing CD38 and melphalan.
摘要翻译: 药物组合物包含特异性识别CD38和美法仑的抗体。
-
10.Antitumor combinations containing antibodies recognizing specifically CD38 and vincristine 有权
标题翻译: 含有特异性识别CD38和长春新碱的抗体的抗肿瘤组合公开(公告)号:US08633301B2
公开(公告)日:2014-01-21
申请号:US13130865
申请日:2009-11-27
申请人: Pascale Lejeune , Patricia Vrignaud
发明人: Pascale Lejeune , Patricia Vrignaud
IPC分类号: C07K16/00 , C12P21/08 , A61K39/395 , A61K39/00
CPC分类号: A61K31/475 , A61K31/00 , A61K39/395 , A61K2300/00
摘要: Pharmaceutical composition comprising an antibody specifically recognizing CD38 and vincristine.
摘要翻译: 药物组合物,其包含特异性识别CD38和长春新碱的抗体。
-
-
-
-
-
-
-
-
-