公开(公告)号：US20080103299A1

公开(公告)日：2008-05-01

申请号：US12004251

申请日：2007-12-19

申请人： Paul Fatheree ,  Martin Linsell ,  Daniel Marquess ,  Daniel Long ,  Jason Chinn ,  Matthew Nodwell ,  Edmund Moran ,  James Aggen

发明人： Paul Fatheree ,  Martin Linsell ,  Daniel Marquess ,  Daniel Long ,  Jason Chinn ,  Matthew Nodwell ,  Edmund Moran ,  James Aggen

IPC分类号： C07D501/18

CPC分类号： C07D519/00 ,  A61K38/00 ,  C07D501/46 ,  C07K9/008

摘要： This invention provides cross-linked glycopeptide-cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.

摘要翻译： 本发明提供可用作抗生素的交联糖肽 - 头孢菌素化合物及其药学上可接受的盐。 本发明还提供含有这些化合物的药物组合物; 使用这些化合物治疗哺乳动物细菌感染的方法; 以及可用于制备这些化合物的方法和中间体。

公开(公告)号：US20060128612A1

公开(公告)日：2006-06-15

申请号：US11342729

申请日：2006-01-30

申请人： Paul Fatheree ,  Martin Linsell ,  Daniel Marquess ,  Daniel Long ,  Jason Chinn ,  Matthew Nodwell ,  Edmund Moran ,  James Aggen

发明人： Paul Fatheree ,  Martin Linsell ,  Daniel Marquess ,  Daniel Long ,  Jason Chinn ,  Matthew Nodwell ,  Edmund Moran ,  James Aggen

IPC分类号： A61K38/14 ,  C07K9/00

CPC分类号： C07D519/00 ,  A61K38/00 ,  C07D501/46 ,  C07K9/008

摘要： This invention provides cross-linked glycopeptide—cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.