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公开(公告)号：US20080103299A1
公开(公告)日：2008-05-01
申请号：US12004251
申请日：2007-12-19
申请人： Paul Fatheree , Martin Linsell , Daniel Marquess , Daniel Long , Jason Chinn , Matthew Nodwell , Edmund Moran , James Aggen
发明人： Paul Fatheree , Martin Linsell , Daniel Marquess , Daniel Long , Jason Chinn , Matthew Nodwell , Edmund Moran , James Aggen
IPC分类号： C07D501/18
CPC分类号： C07D519/00 , A61K38/00 , C07D501/46 , C07K9/008
摘要： This invention provides cross-linked glycopeptide-cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
摘要翻译： 本发明提供可用作抗生素的交联糖肽 - 头孢菌素化合物及其药学上可接受的盐。 本发明还提供含有这些化合物的药物组合物; 使用这些化合物治疗哺乳动物细菌感染的方法; 以及可用于制备这些化合物的方法和中间体。
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公开(公告)号：US20060128612A1
公开(公告)日：2006-06-15
申请号：US11342729
申请日：2006-01-30
申请人： Paul Fatheree , Martin Linsell , Daniel Marquess , Daniel Long , Jason Chinn , Matthew Nodwell , Edmund Moran , James Aggen
发明人： Paul Fatheree , Martin Linsell , Daniel Marquess , Daniel Long , Jason Chinn , Matthew Nodwell , Edmund Moran , James Aggen
CPC分类号： C07D519/00 , A61K38/00 , C07D501/46 , C07K9/008
摘要： This invention provides cross-linked glycopeptide—cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
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公开(公告)号：US20080045721A1
公开(公告)日：2008-02-21
申请号：US11895534
申请日：2007-08-24
申请人： Paul Fatheree , Martin Linsell , Daniel Long , Daniel Marquess , Edmund Moran , Matthew Nodwell , S. Derek Turner , James Aggen
发明人： Paul Fatheree , Martin Linsell , Daniel Long , Daniel Marquess , Edmund Moran , Matthew Nodwell , S. Derek Turner , James Aggen
IPC分类号： C07D277/38
CPC分类号： A61K31/545 , A61K38/00 , C07D277/40 , C07D277/42 , C07D407/12 , C07D407/14 , C07D501/00 , C07D501/46 , C07K9/008
摘要： This invention provides cross-linked glycopeptide-cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
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公开(公告)号：US20080108558A1
公开(公告)日：2008-05-08
申请号：US11977604
申请日：2007-10-25
申请人： Paul Fatheree , Martin Linsell , Daniel Long , Daniel Marquess , Edmund Moran , Matthew Nodwell , S. Derek Turner , James Aggen
发明人： Paul Fatheree , Martin Linsell , Daniel Long , Daniel Marquess , Edmund Moran , Matthew Nodwell , S. Derek Turner , James Aggen
CPC分类号： A61K31/545 , A61K38/00 , C07D277/40 , C07D277/42 , C07D407/12 , C07D407/14 , C07D501/00 , C07D501/46 , C07K9/008
摘要： This invention provides cross-linked glycopeptide—cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
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公开(公告)号：US20080039374A1
公开(公告)日：2008-02-14
申请号：US11895555
申请日：2007-08-24
申请人： Paul Fatheree , Martin Linsell , Daniel Long , Daniel Marquess , Edmund Moran , Matthew Nodwell , S. Derek Turner , James Aggen
发明人： Paul Fatheree , Martin Linsell , Daniel Long , Daniel Marquess , Edmund Moran , Matthew Nodwell , S. Derek Turner , James Aggen
CPC分类号： A61K31/545 , A61K38/00 , C07D277/40 , C07D277/42 , C07D407/12 , C07D407/14 , C07D501/00 , C07D501/46 , C07K9/008
摘要： This invention provides cross-linked glycopeptide—cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
摘要翻译： 本发明提供可用作抗生素的交联糖肽 - 头孢菌素化合物及其药学上可接受的盐。 本发明还提供含有这些化合物的药物组合物; 使用这些化合物治疗哺乳动物细菌感染的方法; 以及可用于制备这些化合物的方法和中间体。
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公开(公告)号：US20080039611A1
公开(公告)日：2008-02-14
申请号：US11895553
申请日：2007-08-24
申请人： Paul Fatheree , Martin Linsell , Daniel Long , Daniel Marquess , Edmund Moran , Matthew Nodwell , S. Derek Turner , James Aggen
发明人： Paul Fatheree , Martin Linsell , Daniel Long , Daniel Marquess , Edmund Moran , Matthew Nodwell , S. Derek Turner , James Aggen
IPC分类号： C07K9/00
CPC分类号： A61K31/545 , A61K38/00 , C07D277/40 , C07D277/42 , C07D407/12 , C07D407/14 , C07D501/00 , C07D501/46 , C07K9/008
摘要： This invention provides cross-linked glycopeptide—cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
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公开(公告)号：US20050239691A1
公开(公告)日：2005-10-27
申请号：US11172303
申请日：2005-06-30
申请人： Paul Fatheree , Martin Linsell , Daniel Long , Daniel Marquess , Edmund Moran , Matthew Nodwell , S. Turner , James Aggen
发明人： Paul Fatheree , Martin Linsell , Daniel Long , Daniel Marquess , Edmund Moran , Matthew Nodwell , S. Turner , James Aggen
IPC分类号： C07D501/46 , A01N37/46 , A61K31/545 , A61K38/00 , A61K38/04 , A61P31/00 , A61P31/04 , C07D277/40 , C07D277/42 , C07D407/12 , C07D407/14 , C07D501/00 , C07D501/14 , C07D501/20 , C07K7/02 , C07K9/00 , A61K38/14
CPC分类号： A61K31/545 , A61K38/00 , C07D277/40 , C07D277/42 , C07D407/12 , C07D407/14 , C07D501/00 , C07D501/46 , C07K9/008
摘要： This invention provides cross-linked glycopeptide-cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
摘要翻译： 本发明提供可用作抗生素的交联糖肽 - 头孢菌素化合物及其药学上可接受的盐。 本发明还提供含有这些化合物的药物组合物; 使用这些化合物治疗哺乳动物细菌感染的方法; 以及可用于制备这些化合物的方法和中间体。
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公开(公告)号：US20060189517A1
公开(公告)日：2006-08-24
申请号：US11405331
申请日：2006-04-17
申请人： Paul Fatheree , Martin Linsell , Daniel Marquess , Sean Trapp , Edmund Moran , James Aggen
发明人： Paul Fatheree , Martin Linsell , Daniel Marquess , Sean Trapp , Edmund Moran , James Aggen
CPC分类号： C07K7/64 , C07D501/00 , C07K9/008
摘要： This invention provides cross-linked glycopeptide—cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
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公开(公告)号：US20050026818A1
公开(公告)日：2005-02-03
申请号：US10888849
申请日：2004-07-09
申请人： Paul Fatheree , Martin Linsell , Daniel Marquess , Sean Trapp , Edmund Moran , James Aggen
发明人： Paul Fatheree , Martin Linsell , Daniel Marquess , Sean Trapp , Edmund Moran , James Aggen
IPC分类号： A61K38/14 , A61P31/04 , C07D501/00 , C07K7/64 , C07K9/00
CPC分类号： C07K7/64 , C07D501/00 , C07K9/008
摘要： This invention provides cross-linked glycopeptide—cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
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公开(公告)号：US20070225329A1
公开(公告)日：2007-09-27
申请号：US11805101
申请日：2007-05-22
申请人： Edmund Moran , John Jacobsen , Michael Leadbetter , Matthew Nodwell , Sean Trapp , James Aggen , Timothy Church
发明人： Edmund Moran , John Jacobsen , Michael Leadbetter , Matthew Nodwell , Sean Trapp , James Aggen , Timothy Church
IPC分类号： A61K31/47
CPC分类号： A61K31/4706 , A61K31/136 , A61K31/277 , A61K31/325 , A61K31/33 , A61K31/343 , A61K31/35 , A61K31/36 , A61K31/381 , A61K31/385 , A61K31/405 , A61K31/4184 , A61K31/423 , A61K31/428 , A61K31/47 , A61K31/4704 , A61K31/4709 , A61K31/58 , C07C213/04 , C07C215/34 , C07C215/60 , C07C217/84 , C07C229/38 , C07C233/43 , C07C317/36 , C07D213/75 , C07D215/227 , C07D215/26 , C07D231/22 , C07D239/38 , C07D239/42 , C07D239/47 , C07D239/69 , C07D277/46 , C07D311/80 , C07D321/10 , C07D401/12 , C07D409/12 , C07D413/12 , A61K2300/00
摘要： The invention provides novel β2 adrenergic receptor agonist compounds of formula (I): wherein R1-R13 and w have any of the values described in the specification. The invention also provides combinations of such compounds and other therapeutic agents, pharmaceutical compositions comprising such compounds and combinations, methods of using such compounds to treat diseases associated with β2 adrenergic receptor activity, and processes and intermediates useful for preparing such compounds.
摘要翻译： 本发明提供新的β2肾上腺素能受体激动剂式（I）化合物：其中R 1 -R 13和w具有任何值 在说明书中描述。 本发明还提供了这些化合物和其它治疗剂的组合，包含这些化合物和组合的药物组合物，使用这些化合物治疗与β2肾上腺素能受体活性有关的疾病的方法，以及可用于 制备此类化合物。
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