公开(公告)号：US06861429B2

公开(公告)日：2005-03-01

申请号：US10212513

申请日：2002-08-05

申请人： Paul John Beswick ,  Charanjit Bountra ,  Ian Baxter Campbell ,  Neil Matthews ,  Alan Naylor

发明人： Paul John Beswick ,  Charanjit Bountra ,  Ian Baxter Campbell ,  Neil Matthews ,  Alan Naylor

IPC分类号： A61K31/00 ,  A61K31/50 ,  A61K31/5025 ,  A61P1/04 ,  A61P3/10 ,  A61P7/06 ,  A61P9/00 ,  A61P11/00 ,  A61P11/06 ,  A61P17/00 ,  A61P17/02 ,  A61P19/02 ,  A61P19/06 ,  A61P25/06 ,  A61P25/16 ,  A61P25/28 ,  A61P27/02 ,  A61P27/16 ,  A61P29/00 ,  A61P35/00 ,  C07D487/04 ,  A61K31/4985

CPC分类号： C07D487/04 ,  A61K31/50 ,  Y02P20/55

摘要： The invention provides a pharmaceutical composition comprising a compound of formula (I) or a pharmaceutically acceptable salt, solvate, ester or salt or solvate of such ester, of a compound of formula (I) in which: R0 is halogen, C1-6alkyl, C1-6alkoxy, C1-6alkoxy substituted by one or more fluorine atoms, or O(CH2)nNR4R5; R1 and R2 are independently selected from H, C1-6alkyl, C1-6alkyl substituted by one or more fluorine atoms, C1-6alkoxy, C1-6hydroxyalkyl, SC1-6alkyl, C(O)H, C(O)C1-6alkyl, C1-6alkylsulphonyl, C1-6alkoxy substituted by one or more fluorine atoms, O(CH2)nCO2C1-6alkyl, O(CH2)nSC1-6alkyl, (CH2)nNR4R5, (CH2)nSC1-6alkyl or C(O)NR4R5; with the proviso that when R0 is at the 4-position and is halogen, at least one of R1 and R2 is C1-6alkylsulphonyl, C1-6alkoxy substituted by one or more fluorine atoms, O(CH2)nCO2C1-6alkyl, O(CH2)nSC1-6alkyl, (CH2)nNR4R5 or (CH2)nSC1-6alkyl, C(O)NR4R5; R3 is C1-6alkyl or NH2; R4 and R5 are independently selected from H and C1-6alkyl or, together with the nitrogen atom to which they are attached, form a 4-8 membered saturated ring; and n is 1-4; and a sodium channel inhibitor.

摘要翻译： 本发明提供包含式（I）化合物或其药学上可接受的盐，溶剂化物，酯或盐或溶剂合物的药物组合物，其中：R 0是卤素，C1 1-6烷基，C 1-6烷氧基，被一个或多个氟原子取代的C 1-6烷氧基，或O（CH 2）n NR 4 R 5; R 1和R 2独立地选自H，C 1-6烷基 被一个或多个氟原子取代的C 1-6烷基，C 1-6烷氧基，C 1-6羟烷基，SC 1-6烷基，C（O）H，C（O）C 1-6烷基，C 1-6烷基磺酰基，被一个或多个 氟原子，O（CH 2）n CO 2 C 1-6烷基，O（CH 2）nSC 1-6烷基，（CH 2）n NR 4 R 5，（CH 2）nSC 1-6烷基或C（O）NR 4 R 5 ; 条件是当R 0在4-位且是卤素时，R 1和R 2中的至少一个是C 1-6烷基磺酰基，被一个或多个氟原子取代的C 1-6烷氧基，O（ O（CH 2）n C 1-6烷基，（CH 2）n NR 4 R 5或（CH 2）nSC 1-6烷基，C（O）NR 4 R 5; R 3， 是C 1-6烷基或NH 2; R 4和R 5独立地选自H和C 1-6烷基，或与它们所连接的氮原子一起形成4-8元饱和环; 和n为1-4;和钠通道抑制剂。

公开(公告)号：US06292187B1

公开(公告)日：2001-09-18

申请号：US09406149

申请日：1999-09-27

申请人： Simon J. Gibbs ,  Neil Matthews

发明人： Simon J. Gibbs ,  Neil Matthews

IPC分类号： G06F300

CPC分类号： H04N21/4431 ,  H04N5/4401 ,  H04N5/44513 ,  H04N7/165 ,  H04N21/23412 ,  H04N21/4351 ,  H04N21/44012 ,  H04N21/4622 ,  H04N21/4782 ,  H04N21/485 ,  H04N21/6547 ,  H04N21/8166

摘要： A method and system for modifying the look and feel of a user interface of a broadcast application program without altering the broadcast application program. In one embodiment, user interfaces are represented as a hierarchical scene including a background and several components. Within an electronic network, broadcast applications can become resident, e.g., land, on a vendor's device within the network where the device has the ability to display a user interface. The present invention provides a set of mattes that can be used to modify the visual presentation of the user interface of a broadcast application without altering the broadcast application. In this way, the vendor of the device can have some level of control regarding the way in which user interfaces are displayed on the device. Each matte controls the way in which an associated component of the user interface is displayed and how the component is combined with other components. In one embodiment, mattes can force components to become semi-transparent thereby creating certain fading effects, special effects with respect to windows in focus, special effects on windows becoming iconified, wiping effects, etc., with respect to the components of the user interface. The present invention can be implemented as a set of application programming interfaces (APIs) which can be used by an application manager of the vendor's device, e.g., a digital television receiver. The APIs would be available to broadcast applications and could be used for visual effects involving elements of an application's user interface.

摘要翻译： 一种用于在不改变广播应用程序的情况下修改广播应用程序的用户界面的外观和感觉的方法和系统。 在一个实施例中，用户界面被表示为包括背景和若干组件的分层场景。 在电子网络内，广播应用可以变得驻留在网络中的供应商设备上，例如设备具有显示用户界面的能力。 本发明提供了可以用于修改广播应用的用户界面的可视呈现而不改变广播应用的一组哑光。 以这种方式，设备的供应商可以对用户界面在设备上的显示方式进行某种程度的控制。 每个遮罩控制显示用户界面的关联组件的方式以及组件与其他组件的组合方式。 在一个实施例中，哑光可以迫使组件变得半透明，从而产生某些衰落效果，关于对焦窗口的特殊效果，关于窗口变成图标的特殊效果，擦拭效果等等。 。 本发明可以被实现为一组应用编程接口（API），其可以由供应商的设备的应用管理器例如数字电视接收机使用。 这些API将可用于广播应用程序，并可用于涉及应用程序用户界面元素的视觉效果。